Evidence map›Paper›PMID 34909650›Full record

ReviewCurrent research in pharmacology and drug discovery2021

Application of coating technology to chronotherapeutic drug delivery systems: Recent publications and patents.

Buduru Gowthami, S V Gopala Krishna, D Subba Rao

Open access · goldAbstract readReview
In one paragraph

Review in Current research in pharmacology and drug discovery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Buduru GowthamiFaculty of Pharmaceutical Sciences, J.N.T.U.A Ananthapuramu, 515002, Andhra Pradesh, India.
S V Gopala KrishnaVagdevi College of Pharmacy and Research Centre, Brahmadevam, Nellore, 524001, Andhra Pradesh, India.
D Subba RaoDept. of Chemical Engineering, J.N.T.U.A Ananthapuramu, 515002, Andhra Pradesh, India.
Jawaharlal Nehru Technological University Anantapur · INSri Ganapathi Sachchidananda Vagdevi Center · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In general, extended release systems have the ability to maintain the drug concentration with in therapeutic range for prolonged period of time, but this may not be the primary requisite for circadian rhythm diseases like asthma, hypertension and rheumatoid arthritis, etc. They require prompt release of drug as per the disease condition, which can be achieved by programmed lag time. Chronotherapeutic drug delivery systems (CDDS) can be achieved by several methods, coating is one amongst them. Though the coating process is complex in terms of methodology, solubility issues and difficulty in achieving the uniform coating, many researchers were successfully employed in development of CDDS. A scientific prospection was made from 2010 to 2020 using PubMed database. Apart from exploration of publication data, we attempt to brief about classification of patents and concordance. The scrutiny also highlights the patents filed on chronotherapeutic systems, focusing particularly on coating technologies. The review is concluded the successful application of coating technology to develop CDDS, as evident from vast number of publications and patents filed.

Indexed as

ChronotherapeuticsCoatingPatentsScientific prospection

Identifiers

PMID34909650
PMCPMC8663946
OpenAlexW3128395325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.