Evidence map›Paper›PMID 34909551›Full record

Article... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision2021

Multi-scanner Harmonization of Paired Neuroimaging Data via Structure Preserving Embedding Learning.

Mahbaneh Eshaghzadeh Torbati, Dana L Tudorascu, Davneet S Minhas, Pauline Maillard, Charles S DeCarli, Seong Jae Hwang

Abstract read
In one paragraph

Article in ... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahbaneh Eshaghzadeh TorbatiUniversity of Pittsburgh.
Dana L TudorascuUniversity of Pittsburgh.
Davneet S MinhasUniversity of Pittsburgh.
Pauline MaillardUniversity of California, Davis.
Charles S DeCarliUniversity of California, Davis.
Seong Jae HwangUniversity of Pittsburgh.

Funding

Research Education ComponentP30AG066468 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN · 2020 to 2026
$29.4M
UC Davis Alzheimer's Disease Core CenterP30AG010129 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI DECARLI, CHARLES · 1991 to 2020
$28.3M
Novel imaging and endothelial biomarkers of small vessel cerebrovascular diseaseUH3NS100608 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DECARLI, CHARLES, KRAMER, JOEL H · 2018 to 2020
$3.5M
Statistical methods to improve reproducibility and reduce technical variability in heterogeneous multimodal neuroimaging studies of Alzheimer’s DiseaseR01AG063752 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TUDORASCU, DANA L · 2019 to 2023
$3.0M
Novel Imaging and Biofluid Biomarkers of Small Vessel Cerebrovascular DiseaseUF1NS100608 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRAMER, JOEL H · 2021 to 2021
$2.5M
NIA NIH HHS P30 AG010129NIA NIH HHS P30 AG066468NIA NIH HHS R01 AG063752NINDS NIH HHS UF1 NS100608NINDS NIH HHS UH3 NS100608
6 · The paper itself

Abstract

Combining datasets from multiple sites/scanners has been becoming increasingly more prevalent in modern neuroimaging studies. Despite numerous benefits from the growth in sample size, substantial technical variability associated with site/scanner-related effects exists which may inadvertently bias subsequent downstream analyses. Such a challenge calls for a data harmonization procedure which reduces the scanner effects and allows the scans to be combined for pooled analyses. In this work, we present MISPEL (Multi-scanner Image harmonization via Structure Preserving Embedding Learning), a multi-scanner harmonization framework. Unlike existing techniques, MISPEL does not assume a perfect coregistration across the scans, and the framework is naturally extendable to more than two scanners. Importantly, we incorporate our multi-scanner dataset where each subject is scanned on four different scanners. This unique paired dataset allows us to define and aim for an ideal harmonization (e.g., each subject with identical brain tissue volumes on all scanners). We extensively view scanner effects under varying metrics and demonstrate how MISPEL significantly improves them.

Identifiers

PMID34909551
PMCPMC8668020

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.