Evidence map›Paper›PMID 34909108›Full record

ArticleThe Pan African medical journal2021

The prevalence and pattern of antibiotic prescription among insured patients in Dar es Salaam Tanzania.

Mohamed Ally Khalfan, Philip Galula Sasi, Sabina Ferdinand Mugusi

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Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

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9citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

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9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

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3 authors.

Mohamed Ally KhalfanDepartment of Clinical Pharmacology, School of Medicine, Muhimbili University of Health and Allied Health Sciences, Dar es Salaam, Tanzania.
Philip Galula SasiDepartment of Clinical Pharmacology, School of Medicine, Muhimbili University of Health and Allied Health Sciences, Dar es Salaam, Tanzania.
Sabina Ferdinand MugusiDepartment of Clinical Pharmacology, School of Medicine, Muhimbili University of Health and Allied Health Sciences, Dar es Salaam, Tanzania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionhigh prevalence of antibiotic prescriptions may contribute to the problem of antibiotic resistance. Understanding the pattern of antibiotic prescriptions in a country may inform monitoring and stewardship activities, which are crucial in the fight against antibiotic resistance. We aimed to determine the prevalence and describe the pattern of antibiotic prescriptions among National Health Insurance Fund (NHIF) insured patients receiving treatment at health facilities in Ilala Municipality, Dar es Salaam, Tanzania.

methodsa cross-sectional analysis of claim forms of NHIF insured patients. A data extraction form was used to capture data for September, 2019 submitted to the Ilala NHIF offices.

resultsamong 993 insured patients (mean [±SD] age 36.3 [±23.2] years; 581 [58.5%] females; 535 [53.9%] adults) a total of 357 (46.4%, 95% CI, 42.8-50.0) received an antibiotic prescription. Of the 357 patients who received an antibiotic prescription, 71(19.9%) received more than one antibiotic prescription. The most common antibiotic prescribed was amoxicillin/clavulanate (17.1%) followed by amoxicillin (16.5%) whereas the most commonly prescribed antibiotic class was the penicillins (51.3%) followed by the nitroimidazoles (14.0%). Among patients who received more than one antibiotic, the most commonly co-prescribed antibiotics were Ampicillin/Cloxacillin plus Metronidazole (11.4%) followed by Amoxicillin plus Metronidazole (7.1%). According to 2019 WHO Access, Watch, Reserve (AWaRe) Classification of antibiotics, 60.8% of patients received the access antibiotics, 33.3% received the watch antibiotics whereas 17.4% of patients received antibiotics that were not recommended. No patient received an antibiotic from the reserve group.

conclusionthe prevalence of antibiotic prescriptions in Tanzania is high and some antibiotics not recommended by the WHO are still prescribed. We recommend revision of the current Tanzania treatment guideline on antibiotics to reflect WHO recommendations, and further research to address local factors influencing antibiotic prescriptions is warranted.

Indexed as

Anti-Bacterial AgentsPrescriptionsAdultCross-Sectional StudiesFemaleHumansPrevalenceTanzaniaAnti-Bacterial Agents2019 WHO AWaRe classificationantibiotic prescription patternAntibiotic prescription prevalence

Identifiers

PMID34909108
PMCPMC8641635

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