Evidence map›Paper›PMID 34909067›Full record

ArticleArabian journal of chemistry2022

A possible potential COVID-19 drug candidate: Diethyl 2-(2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetyl)hydrazono)malonate: Docking of disordered independent molecules of a novel crystal structure, HSA/DFT/XRD and cytotoxicity.

Mohcine Missioui, Musa A Said, Güneş Demirtaş, Joel T Mague, Ahlam Al-Sulami, Nadia S Al-Kaff, Youssef Ramli

Abstract read
In one paragraph

Article in Arabian journal of chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Synthesis, crystal structure and Hirshfeld surface analysis of 2-phenyl-3-(prop-2-yn-1-yl-oxy)quin-oxaline.Acta crystallographica. Section E, Crystallographic communications · 2024
    Article
  6. Article
  7. Crystal structure and Hirshfeld surface analysis ofActa crystallographica. Section E, Crystallographic communications · 2022
    Article
  8. Crystal structure and Hirshfeld surface analysis of 2-azido-Acta crystallographica. Section E, Crystallographic communications · 2022
    Article
  9. 2-Azido-IUCrData · 2022
    Article
  10. Crystal structure and Hirshfeld surface analysis of 2-chloro-Acta crystallographica. Section E, Crystallographic communications · 2022
    Article
  11. Article
  12. Synthesis,Journal of molecular structure · 2022
    Article
  13. Crystal structure and Hirshfeld surface analysis of (Acta crystallographica. Section E, Crystallographic communications · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohcine MissiouiLaboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.
Musa A SaidCollege of Science, Taibah University, PO Box 30002, Al-Madinah Al Munawarah, 1417, Saudi Arabia.
Güneş DemirtaşOndokuz Mayıs University, Faculty of Arts and Sciences, Department of Physics, 55139 Samsun, Turkey.
Joel T MagueDepartment of Chemistry, Tulane University, New Orleans, LA 70118, USA.
Ahlam Al-SulamiDepartment of Chemistry, College of Science, University of Jeddah, Jeddah 21589, Saudi Arabia.
Nadia S Al-KaffCollege of Science, Taibah University, PO Box 30002, Al-Madinah Al Munawarah, 1417, Saudi Arabia.
Youssef RamliLaboratory of Medicinal Chemistry, Drug Sciences Research Center, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports the synthesis, characterization and importance of a novel diethyl 2-(2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetyl)hydrazono)malonate (

Indexed as

ADMETCOVID-19Crystal structureDFTHirshfeld surface analysis (HSA)In silico molecular dockingMalonate-based quinoxalinePASS

Identifiers

PMID34909067
PMCPMC8627592

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.