Evidence map›Paper›PMID 34909048›Full record

ArticleResearch in pharmaceutical sciences2022

Design, synthesis, and molecular docking of cysteine-based sulphonamide derivatives as antimicrobial agents.

Melford C Egbujor, Uchechukwu C Okoro, Sunday N Okafor, Samuel A Egu, Ifeanyi S Amasiatu, Pius I Egwuatu, Odera R Umeh, Eziafakaego M Ibo

Open access · goldAbstract read
In one paragraph

Article in Research in pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Organosulfur Compounds: Potential Therapeutics for Parkinson's Disease.CNS & neurological disorders drug targets · 2026
    Review
  4. Review
  5. Article
  6. Sulfonamide Derivatives: Recent Compounds with Potent Anti-alzheimer's Disease Activity.Central nervous system agents in medicinal chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Melford C EgbujorDepartment of Industrial Chemistry, Renaissance University, Ugbawka, Enugu State, Nigeria.
Uchechukwu C OkoroSynthetic Organic Chemistry Division, Department of Pure and Industrial Chemistry, University of Nigeria, Nsukka, Enugu State, Nigeria.
Sunday N OkaforDepartment of Pharmaceutical and Medicinal Chemistry, University of Nigeria, Nsukka, Enugu State, Nigeria.
Samuel A EguDepartment of Pure and Industrial Chemistry, Kogi State University, Anyigba, Kogi State, Nigeria.
Ifeanyi S AmasiatuDepartment of Biochemistry, Renaissance University, Ugbawka, Enugu State, Nigeria.
Pius I EgwuatuDepartment of Microbiology, Renaissance University, Ugbawka, Enugu State, Nigeria.
Odera R UmehDepartment of Applied Microbiology and Brewing, Nnamdi Azikiwe University, P.M.B 5025 Awka, Anambra State, Nigeria.
Eziafakaego M IboDepartment of Applied Microbiology and Brewing, Nnamdi Azikiwe University, P.M.B 5025 Awka, Anambra State, Nigeria.
Renaissance University · NGNnamdi Azikiwe University · NGUniversity of Nigeria · NGKogi State University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe preponderance of microbial infections remains a global challenge. In the present study, synthesis of novel cysteine-based antimicrobial agents and their biological evaluation is reported. EXPERIMENTAL APPROACH: The reaction of FINDINGS/

resultsCompounds CONCLUSION AND IMPLICATION: All the synthesized compounds exhibited significant antibacterial and antifungal activities and were confirmed to be potential antimicrobial agents.

Indexed as

Antimicrobial activityCarboxamideCysteineMolecular dockingSulphonamide

Identifiers

PMID34909048
PMCPMC8621839
OpenAlexW3213499034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.