Evidence map›Paper›PMID 34909035›Full record

ArticleClinical neuropsychiatry2021

Deontological Guilt and Disgust Sensitivity Modulate Moral Behaviour.

Irene Parisi, Alessandra Mancini, Francesco Mancini, Salvatore Maria Aglioti, Maria Serena Panasiti

Open access · greenAbstract read
In one paragraph

Article in Clinical neuropsychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Risk management during times of health uncertainty in Spain: A qualitative analysis of ethical challenges.Risk analysis : an official publication of the Society for Risk Analysis · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Irene ParisiCenter for Life Nano- & Neuro-Science, Istituto Italiano di Tecnologia, Rome & Sapienza University of Rome.
Alessandra ManciniScuola di Specializzazione in Psicoterapia Cognitiva APC-SPC, Rome, Italy.
Francesco ManciniScuola di Specializzazione in Psicoterapia Cognitiva APC-SPC, Rome, Italy.
Salvatore Maria AgliotiCenter for Life Nano- & Neuro-Science, Istituto Italiano di Tecnologia, Rome & Sapienza University of Rome.
Maria Serena PanasitiSocial Neuroscience Laboratory, IRCCS Fondazione Santa Lucia, Via Ardeatina, 306 - 00179.
Marconi University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDeontological Guilt (DG), and Altruistic Guilt (AG) emerge from the appraisal of violating an internalized rule or an altruistic principle, respectively. DG is strictly connected with Disgust Sensitivity and plays a key role in the development and maintenance of Obsessive-Compulsive Disorder (OCD). Previous studies investigated how DG affects responses to hypothetical moral dilemmas, however how DG and Disgust Sensitivity interact modulating moral behavior is still unknown.

methodsSTUDY 1. 46 healthy participants performed an ecological paradigm in which people can spontaneously decide to lie to obtain a reward (egoistic lie) or give it away (altruistic lie) after three emotional inductions: DG, AG or neutral. Furthermore, OCD traits, Morality, Guilt Propensity and Disgust Sensitivity were assessed by means of questionnaires. STUDY 2. 27 participants from the original sample were retested during the COVID-19 lockdown in Italy to ascertain whether the pandemic modified traits related to morality, disgust, guilt or OCD symptoms and whether these changes modulated moral behavior (measured by a task in which cheating was associated to higher pay-offs).

resultsSTUDY 1. Compared to the neutral, after the DG induction participants produced less altruistic and more egoistic lies. This effect was stronger in participants with high Disgust Sensitivity. STUDY 2. During the COVID-19 lockdown participants became more sensitive to the Authority pillar of the Moral Foundations and more sensitive to Disgust: this increment in deontological morality affected (im) moral behavior depending on changes in Disgust Sensitivity.

conclusionsOur data suggest that people with high Disgust Sensitivity are more affected by deontological inductions which translate to higher immorality, supposedly by lowering their moral self-image. These results might have important clinical implications as they suggest that addressing Disgust Sensitivity in therapy, might also decrease the effect of guilt on patients' behavior.

Indexed as

deontological guiltdisgust sensitivitymoral behaviourobsessive-compulsive disorder

Identifiers

PMID34909035
PMCPMC8650176
OpenAlexW3209227496

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.