Evidence map›Paper›PMID 34909008›Full record

ArticleClinical neuropsychiatry2020

Bipolar Disorder Treatments and Ovarian Cancer: A Systematic Review.

Mario Miniati, Ciro Conversano, Laura Palagini, Beatrice Buccianelli, Mariagrazia Fabrini, Maricia Mancino, Concetta Laliscia, Donatella Marazziti, Fabiola Paiar, Angelo Gemignani

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical neuropsychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mario MiniatiDepartment of Clinical and Experimental Medicine, University of Pisa, 57 Via Roma, Italy.
Ciro ConversanoDepartment of Surgical Pathology, Medical, Molecular and Critical Area, University of Pisa, 57 Via Roma, Pisa, Italy.
Laura PalaginiDepartment of Clinical and Experimental Medicine, University of Pisa, 57 Via Roma, Italy.
Beatrice BuccianelliDepartment of Clinical and Experimental Medicine, University of Pisa, 57 Via Roma, Italy.
Mariagrazia FabriniDepartment of Radiotherapy, University of Pisa, 57 Via Roma, Pisa, Italy.
Maricia MancinoDepartment of Radiotherapy, University of Pisa, 57 Via Roma, Pisa, Italy.
Concetta LalisciaDepartment of Radiotherapy, University of Pisa, 57 Via Roma, Pisa, Italy.
Donatella MarazzitiDepartment of Clinical and Experimental Medicine, University of Pisa, 57 Via Roma, Italy.
Fabiola PaiarDepartment of Radiotherapy, University of Pisa, 57 Via Roma, Pisa, Italy.
Angelo GemignaniDepartment of Surgical Pathology, Medical, Molecular and Critical Area, University of Pisa, 57 Via Roma, Pisa, Italy.
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe reviewed literature on drugs for bipolar disorders (BD), utilized in ovarian cancer (OC).

methodWe adhered to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines in completion of this systematic review.

resultsWe identified 73 papers. Thirty-two studies were finally included. BD is rarely diagnosed in OC patients. Limited finding from case reports is available. Drugs used to treat BD (mainly lithium and valproic acid) have been extensively studied in add-on to chemotherapy for treatment-resistant OC cells or in animal models, with promising results in vitro but not in vivo.

conclusionsThe clinical underestimation of BD in OC has leaded to the almost complete absence of evidences for a soundly based clinical guidance in this field. There is a urgent need for a systematic multi-disciplinary approach to OC.

Indexed as

atypical neurolepticsbipolar disordersmood stabilizersovarian cancerpsychopharmacology

Identifiers

PMID34909008
PMCPMC8629050
OpenAlexW4206465669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.