Evidence map›Paper›PMID 34909002›Full record

ArticleClinical neuropsychiatry2020

Lifetime Psychiatric Comorbidity and Diagnostic Trajectories in an Italian Psychiatric Sample.

Antonio Bruno, Antonella Mattei, Federico Arnone, Arianna Barbieri, Valerio Basile, Clemente Cedro, Laura Celebre, Carmela Mento, Amelia Rizzo, Maria Catena Silvestri and 3 more

Open access · greenAbstract read
In one paragraph

Article in Clinical neuropsychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Wanna Bet? Investigating the Factors Related to Adolescent and Young Adult Gambling.European journal of investigation in health, psychology and education · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Antonio BrunoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Antonella MatteiDepartment of Health, Life and Environmental Sciences, University of L'Aquila, Italy.
Federico ArnoneDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Arianna BarbieriDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Valerio BasileDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Clemente CedroDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Laura CelebreDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Carmela MentoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Amelia RizzoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Maria Catena SilvestriDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Maria Rosaria Anna MuscatelloDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Rocco Antonio ZoccaliDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
Gianluca PandolfoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.
University of Messina · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveComorbidity in psychiatric patients has been widely examined in the literature, enucleating the role in misinterpretation of symptom's root in a multi-disease background, as well as the impact on the quality of life, outcome, and health-care effects. This research aimed to examine, in an Italian population of psychiatric patients, the diagnostic continuum in the context of lifetime psychiatric comorbidity, assessing possible differences related to the onset disorder.

methodA retrospective analysis of medical records of 458 subjects, in which various psychiatric diagnoses were represented and categorized in 16 nosographic classes, was conducted.

resultsResults showed that "Bipolar disorder" (22.06%) was the most frequent diagnosis, "Eating disorder" had the earliest age onset (Mean age years = 16 ± 1.41), and "Schizophrenia" showed the longest disease duration (Mean years = 24.20±12.76). Moreover, 54,4% of the final sample presented at least one psychiatric comorbidity in disease history, while "Other personality disorders" was the most comorbidity-associated diagnosis, representing 29% of all the cases with more than 3 past diagnoses. Heterotypic transition was observed in fairly all considered onset diagnoses, exception made for "Schizophrenia" with 75% of the subjects showing homotypic progression.

conclusionsOur results suggest a tendency to make multiple diagnoses over psychiatric patients' lifetime in the majority of cases, often escaping from the original onset nosographic domain. More generally, our findings agree with a broad consensus that describes psychiatric symptomatic dimensions rather overlapped and correlated with each other, leading to a more transdiagnostic clinical approach.

Indexed as

comorbiditydiagnostic trajectoriesheterotypic patternhomotypic pattern

Identifiers

PMID34909002
PMCPMC8629092
OpenAlexW4206096984

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.