Evidence map›Paper›PMID 34908858›Full record

ReviewClinical and experimental gastroenterology2021

Emerging Data on Fistula Laser Closure (FiLaC) for the Treatment of Perianal Fistulas; Patient Selection and Outcomes.

Samuel O Adegbola, Kapil Sahnan, Phillip Tozer, Janindra Warusavitarne

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Clinical and experimental gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07452666 (FISTULA-RFA Trial), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07452666 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

FISTULA-RFA Trial (Fistula Inactivation by Segmental Thermal Uniform Lesion Ablation-Radiofrequency Ablation): A Prospective, Multicenter, Single-Arm Pilot Study in Patients With Perianal Fistula

TypeinterventionalSponsorKorea University Ansan HospitalRan2026 to 2027Enrolled80ConditionsRectal FistulasArmsRadiofrequency Ablation (RFA) for Perianal Fistula
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Evidence outside the box: Minimally invasive treatment for anal fistula.World journal of gastrointestinal surgery · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samuel O AdegbolaRobin Phillips Fistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.ORCID 0000-0003-2522-3895
Kapil SahnanRobin Phillips Fistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
Phillip TozerRobin Phillips Fistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
Janindra WarusavitarneRobin Phillips Fistula Research Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
St Mark's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fistula laser closure (FiLaC) is a relatively new sphincter-sparing technique in fistula surgery that was initially reported in 2011. It involves the radial dissipation of laser energy in the fistula tract and, through a combination of coagulation and shrinkage of the tract, is proposed to result in progressive sealing of fistulas. Early studies have suggested minimal impact on continence and touted the advantage of minimal morbidity with potential of repeat procedures if the technique fails initially. Despite early promising results, ten years on, questions remain on the technique, patient selection and long-term outcomes. This narrative review assesses the evidence reported to-date of radially emitting laser fistula surgery in the treatment of perianal fistulas.

Indexed as

FiLaCfistulafistula laser closureperianal Crohn’s diseaseperianal fistulasurgery

Identifiers

PMID34908858
PMCPMC8664604
OpenAlexW4200408596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.