Evidence map›Paper›PMID 34908846›Full record

ArticleJournal of asthma and allergy2021

A Multicenter Study Assessing Risk Factors and Aeroallergens Sensitization Characteristics in Children with Self-Reported Allergic Rhinitis in China.

Liting Wu, Wenting Luo, Haisheng Hu, Xianhui Zheng, Zhangkai J Cheng, Dongming Huang, Xiaowen Huang, Hong Zhang, Yang Liu, Rongfang Zhang and 13 more

Open access · goldAbstract read
In one paragraph

Article in Journal of asthma and allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Evolution of IgE sensitization profiles toThe World Allergy Organization journal · 2026
    Article
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  4. Landscape of Aeroallergen Sensitization in Asia.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 9 institutions in 1 country.

Liting Wu *Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.
Wenting Luo *Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.
Haisheng HuDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.
Xianhui ZhengDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.ORCID 0000-0002-0385-7523
Zhangkai J ChengDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.ORCID 0000-0002-8621-4119
Dongming HuangDepartment of Pediatrics, Boai Hospital of Zhongshan City, Zhongshan, 528400, People's Republic of China.
Xiaowen HuangDepartment of Pediatrics, Boai Hospital of Zhongshan City, Zhongshan, 528400, People's Republic of China.
Hong ZhangGansu Provincial Hospital, Lanzhou, 730000, People's Republic of China.
Yang LiuGansu Provincial Hospital, Lanzhou, 730000, People's Republic of China.
Rongfang ZhangGansu Provincial Maternity and Child Care Hospital, Lanzhou, 730000, People's Republic of China.
Hui YangGansu Provincial Maternity and Child Care Hospital, Lanzhou, 730000, People's Republic of China.
Yun SunYinchuan Maternal and Child Health Care Hospital, Yinchuan, 750000, People's Republic of China.
Yi WangYinchuan Maternal and Child Health Care Hospital, Yinchuan, 750000, People's Republic of China.
JinHai MaNingxia Medical University General Hospital, Yinchuan, 750000, People's Republic of China.
Jing LiuNingxia Medical University General Hospital, Yinchuan, 750000, People's Republic of China.
Xin SunDepartment of Pediatrics, Xijing Hospital, the Fourth Military Medical University, Xian, 710032, People's Republic of China.
Huajie WuDepartment of Pediatrics, Xijing Hospital, the Fourth Military Medical University, Xian, 710032, People's Republic of China.
Chunhua WeiWeifang Weien Hospital, Weifang, 261000, People's Republic of China.
Shuping ZhangWeifang Weien Hospital, Weifang, 261000, People's Republic of China.
Xiaoluan LiThe First Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.
Shuang RenThe First Hospital of Hebei Medical University, Shijiazhuang, 050000, People's Republic of China.
Chuangli HaoDepartment of Respirology, Children's Hospital, Soochow University, Suzhou, 215025, People's Republic of China.
Baoqing SunDepartment of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, 510120, People's Republic of China.ORCID 0000-0002-1671-0723
First Affiliated Hospital of Guangzhou Medical University · CNBoai Hospital of Zhongshan · CNGansu Provincial Hospital · CNGansu Provincial Maternal and Child Health Hospital · CNHebei Medical University · CNNingxia Medical University · CNXijing Hospital · CNYinchuan First People's Hospital · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUp to now, epidemiological studies on allergy rhinitis (AR) have primarily focused on determining the risk of disease in Chinese adults, with the majority of them designed by single centers, while cross-sectional and epidemiological data describing allergic sensitization in children with self-reported AR are scarce.

objectiveThis study was estimating of the latest information about the sensitization patterns and risk factors of clinical AR to develop effective strategies for the prevention and treatment of AR.

methodsWe conducted a cross-sectional survey between January 2020 and June 2021 involving children from seven cities in China who reported AR. A total of 762 children participated in this survey. To evaluate the risk factors and specific sensitization patterns of clinical AR through questionnaires and specific immunoglobulin E to 11 aeroallergens.

resultsOf the 762 patients, 593 (77.8%) had at least one positive IgE level. Aged 7-14 years (OR 1.503, (95% CI 1.058-2.136),

conclusionThere was an apparent geographic variation in childhood allergies in China. Age factors also had strong impacts on the allergen sensitization rate of children, but these impacts differed across regions.

Indexed as

aeroallergenallergic rhinitischildrencross-sectional surveyspecific immunoglobulin E

Identifiers

PMID34908846
PMCPMC8665874
OpenAlexW4200336493

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.