Evidence map›Paper›PMID 34908760›Full record

ArticleAsian journal of transfusion science

Case report and strategies to mitigate passive hemolysis with platelet transfusions in children.

Merline Augustine, Mohandoss Murugesan, Kaduveettil Gopinathan Gopakumar, T K Jithin

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. How do we transfuse children in Italy? Results of a national survey.Blood transfusion = Trasfusione del sangue · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Merline AugustineDivision of Transfusion Medicine, Malabar Cancer Centre, Thalassery, Kerala, India.
Mohandoss MurugesanDivision of Transfusion Medicine, Malabar Cancer Centre, Thalassery, Kerala, India.
Kaduveettil Gopinathan GopakumarDivision of Pediatric Oncology, Malabar Cancer Centre, Thalassery, Kerala, India.
T K JithinDivision of Pediatric Oncology, Malabar Cancer Centre, Thalassery, Kerala, India.
Malabar Cancer Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mismatched platelet concentrate transfusion due to inadequately maintained inventories is relatively common and in most instances do not cause any untoward event in adults. The cases of passive hemolysis following a mismatched apheresis platelet transfusion are common but are relatively rare with platelet concentrates. We report here a case of a nine year old boy who received three units of mismatched platelet concentrates(PC) followed by acute hemolysis. On further investigation, one of the donors of the PC, who was typed as O positive, found to have high anti-A and anti-B titres of 1:128. This highlights the importance of matched platelet transfusions or modifying the product in pediatric setting, who are susceptible for passive hemolysis.

Indexed as

ABO-incompatibleplatelet transfusionstransfusion reaction

Identifiers

PMID34908760
PMCPMC8628241
OpenAlexW4225963827

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.