Evidence map›Paper›PMID 34908514›Full record

ArticleCancer biology & therapy2021

STAT1 mediated long non-coding RNA LINC00504 influences radio-sensitivity of breast cancer via binding to TAF15 and stabilizing CPEB2 expression.

Jinchun Feng, Yan Li, Liping Zhu, Qian Zhao, Dan Li, Yuxiang Li, Tao Wu

Open access · bronzeAbstract read
In one paragraph

Article in Cancer biology & therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
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  4. Non-coding RNAs modulation in breast cancer radioresponse: mechanisms and therapeutic implications.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jinchun FengDepartment of Breast Surgery, Cancer Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, China.
Yan LiDepartment of Breast Surgery, Hami City Second People's Hospital, Hami, Xinjiang, China.
Liping ZhuDepartment of Breast Surgery, Cancer Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, China.
Qian ZhaoDepartment of Breast Surgery, Cancer Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, China.
Dan LiDepartment of Breast Surgery, Cancer Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, China.
Yuxiang LiDepartment of Breast Surgery, Cancer Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, China.
Tao WuDepartment of Breast Surgery, Cancer Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, China.ORCID 0000-0002-5350-2165
Xinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy plays important roles in the treatment of breast cancer (BC), which develops from malignant cells in the breast. Long non-coding RNAs (lncRNAs) have been reported to be implicated in radio-resistance or radio-sensitivity of human cancer, which includes breast cancer. Nevertheless, long intergenic non-protein coding RNA 0504 (LINC00504) has not been investigated in BC. In our study, from RT-qPCR analysis, LINC00504 was found to be up-regulated in BC cells. By conducting

Indexed as

Breast NeoplasmsRNA, Long NoncodingTATA-Binding Protein Associated FactorsBreastFemaleGene Expression Regulation, NeoplasticHumansRNA-Binding ProteinsSTAT1 Transcription FactorUp-RegulationCPEB2 protein, humanRNA-Binding ProteinsRNA, Long NoncodingSTAT1 protein, humanSTAT1 Transcription FactorTAF15 protein, humanTATA-Binding Protein Associated FactorsBreast cancerCPEB2LINC00504radio-sensitivityTAF15

Identifiers

PMID34908514
PMCPMC8726690
OpenAlexW4200345734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.