Evidence map›Paper›PMID 34908478›Full record

ArticleThe British journal of radiology2022

Deep-learning reconstruction for ultra-low-dose lung CT: Volumetric measurement accuracy and reproducibility of artificial ground-glass nodules in a phantom study.

Ryoji Mikayama, Takashi Shirasaka, Tsukasa Kojima, Yuki Sakai, Hidetake Yabuuchi, Masatoshi Kondo, Toyoyuki Kato

Abstract readComparative Study
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryoji MikayamaDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
Takashi ShirasakaDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
Tsukasa KojimaDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
Yuki SakaiDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
Hidetake YabuuchiDepartment of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.
Masatoshi KondoDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.
Toyoyuki KatoDivision of Radiology, Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe lung nodule volume determined by CT is used for nodule diagnoses and monitoring tumor responses to therapy. Increased image noise on low-dose CT degrades the measurement accuracy of the lung nodule volume. We compared the volumetric accuracy among deep-learning reconstruction (DLR), model-based iterative reconstruction (MBIR), and hybrid iterative reconstruction (HIR) at an ultra-low-dose setting.

methodsArtificial ground-glass nodules (6 mm and 10 mm diameters, -660 HU) placed at the lung-apex and the middle-lung field in chest phantom were scanned by 320-row CT with the ultra-low-dose setting of 6.3 mAs. Each scan data set was reconstructed by DLR, MBIR, and HIR. The volumes of nodules were measured semi-automatically, and the absolute percent volumetric error (APEvol) was calculated. The APEvol provided by each reconstruction were compared by the Tukey-Kramer method. Inter- and intraobserver variabilities were evaluated by a Bland-Altman analysis with limits of agreements.

resultsDLR provided a lower APEvol compared to MBIR and HIR. The APEvol of DLR (1.36%) was significantly lower than those of the HIR (8.01%,

conclusionsDLR showed higher accuracy compared to MBIR and HIR for the volumetric measurement of artificial ground-glass nodules by ultra-low-dose CT. ADVANCES IN KNOWLEDGE: DLR with ultra-low-dose setting allows a reduction of dose exposure, maintaining accuracy for the volumetry of lung nodule, especially in patients which deserve a long-term follow-up.

Indexed as

Deep LearningPhantoms, ImagingHumansLung NeoplasmsRadiation DosageRadiation ExposureRadiographic Image EnhancementSolitary Pulmonary NoduleTomography, X-Ray ComputedTumor Burden

Identifiers

PMID34908478
PMCPMC8822562

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.