Evidence map›Paper›PMID 34908459›Full record

ArticlemSphere2021

Understanding Lactobacillus paracasei and Streptococcus oralis Biofilm Interactions through Agent-Based Modeling.

Linda Archambault, Sherli Koshy-Chenthittayil, Angela Thompson, Anna Dongari-Bagtzoglou, Reinhard Laubenbacher, Pedro Mendes

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Control of medical digital twins with artificial neural networks.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Linda Archambault *Center for Quantitative Medicine, University of Connecticutgrid.208078.5grid.63054.34 School of Medicine, Farmington, Connecticut, USA.ORCID 0000-0003-0205-9463
Sherli Koshy-Chenthittayil *Center for Quantitative Medicine, University of Connecticutgrid.208078.5grid.63054.34 School of Medicine, Farmington, Connecticut, USA.
Angela ThompsonDepartment of Oral Health and Diagnostic Sciences, University of Connecticutgrid.208078.5grid.63054.34 School of Dental Medicine, Farmington, Connecticut, USA.
Anna Dongari-BagtzoglouDepartment of Oral Health and Diagnostic Sciences, University of Connecticutgrid.208078.5grid.63054.34 School of Dental Medicine, Farmington, Connecticut, USA.
Reinhard LaubenbacherDepartment of Medicine, University of Florida, Gainesville, Florida, USA.
Pedro MendesCenter for Quantitative Medicine, University of Connecticutgrid.208078.5grid.63054.34 School of Medicine, Farmington, Connecticut, USA.
University of Connecticut · USUniversity of Florida · US

Funding

Oral Epithelial Cells, Candida and PMN ActivationR01DE013986 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Anna I Dongari-Bagtzoglou · 2000 to 2026
$9.2M
Multiscale modeling of the role of heme during invasive pulmonary aspergillosisR01AI135128 · NIAID · UNIVERSITY OF FLORIDA · PI REINHARD LAUBENBACHER, Borna Mehrad · 2018 to 2026
$4.9M
Modular design of multiscale models, with an application to the innate immune response to fungal respiratory pathogens.U01EB024501 · NIBIB · UNIVERSITY OF FLORIDA · PI LAUBENBACHER, REINHARD, MEHRAD, BORNA · 2017 to 2020
$2.9M
Control of heterogeneous microbial communities using model-based multi-objective optimizationR01GM127909 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI DONGARI-BAGTZOGLOU, ANNA I, LAUBENBACHER, REINHARD · 2018 to 2021
$1.8M
NIAID NIH HHS R01 AI135128NIBIB NIH HHS U01 EB024501NIDCR NIH HHS R01 DE013986NIGMS NIH HHS R01 GM127909
6 · The paper itself

Abstract

As common commensals residing on mucosal tissues,

Indexed as

Systems AnalysisBiofilmsLacticaseibacillus paracaseiStreptococcus oralisVirulenceagent-based modelingbiofilmcomputational modelingLactobacillus paracaseioral healthStreptococcus oralis

Identifiers

PMID34908459
PMCPMC8673396
OpenAlexW4225976452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.