Evidence map›Paper›PMID 34908440›Full record

ArticleJournal of virology2022

Susceptibility of Human and Murine Dermal Fibroblasts to Herpes Simplex Virus 1 in the Absence and Presence of Extracellular Matrix.

Lisa Wirtz, Nydia C De La Cruz, Maureen Möckel, Dagmar Knebel-Mörsdorf

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lisa WirtzCenter for Biochemistry, University Hospital Cologne, University of Cologne, Cologne, Germany.
Nydia C De La CruzCenter for Biochemistry, University Hospital Cologne, University of Cologne, Cologne, Germany.
Maureen MöckelCenter for Biochemistry, University Hospital Cologne, University of Cologne, Cologne, Germany.
Dagmar Knebel-MörsdorfCenter for Biochemistry, University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0002-0038-5030
University of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus 1 (HSV-1) invades its human host via the skin and mucosa and initiates infection in the epithelium. While human and murine epidermis are highly susceptible to HSV-1, we recently observed rare infected cells in the human dermis and only minor infection efficiency in murine dermis upon

Indexed as

AnimalsCollagenDermisExtracellular MatrixFibroblastsHerpesvirus 1, HumanHumansMiceNectinsSpecies SpecificityVirus InternalizationCollagenNectinscollagen matricesdermal fibroblastsdermisHSV-1HVEMlatex beadsnectin-1viral entry

Identifiers

PMID34908440
PMCPMC8865408
OpenAlexW4200120581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.