Evidence map›Paper›PMID 34908395›Full record

ArticleACS biomaterials science & engineering2022

Customized Flagelliform Spidroins Form Spider Silk-like Fibers at pH 8.0 with Outstanding Tensile Strength.

Xue Li, Xingmei Qi, Yu-Ming Cai, Yuan Sun, Rui Wen, Rui Zhang, Jan Johansson, Qing Meng, Gefei Chen

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xue LiDepartment of Medical Ultrasound, Shanghai Tenth People's Hospital, Ultrasound Research and Education Institute, Tongji University Cancer Center, Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment, Tongji University School of Medicine, 200092 Shanghai, China.
Xingmei QiThe Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou 215123, China.
Yu-Ming CaiInstitute for Life Sciences, University of Southampton, SO17 1BJ Southampton, Hampshire, U.K.
Yuan SunInstitute of Biological Sciences and Biotechnology, Donghua University, 201620 Shanghai, China.
Rui WenInstitute of Biological Sciences and Biotechnology, Donghua University, 201620 Shanghai, China.
Rui ZhangDepartment of Pulmonary Circulation, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
Jan JohanssonDepartment of Biosciences and Nutrition, Karolinska Institutet, 14157 Huddinge, Sweden.ORCID 0000-0002-8719-4703
Qing MengInstitute of Biological Sciences and Biotechnology, Donghua University, 201620 Shanghai, China.
Gefei ChenDepartment of Biosciences and Nutrition, Karolinska Institutet, 14157 Huddinge, Sweden.ORCID 0000-0002-5543-5963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spider flagelliform silk shows the best extensibility among various types of silk, but its biomimetic preparation has not been much studied. Herein, five customized flagelliform spidroins (FlSps: S and NTD

Indexed as

FibroinsHydrogen-Ion ConcentrationProtein Structure, SecondaryTensile StrengthFibroinscustomized FlSpflagelliformmanual pullingmechanical propertiessilk formation at pH 8.0

Identifiers

PMID34908395
PMCPMC8753598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.