Evidence map›Paper›PMID 34908201›Full record

ArticleClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2022

Increased nasal epithelial cell responsiveness to IL-17A in paediatric asthmatics with low blood neutrophil count, low traffic-related air pollution exposure and good asthma control.

Jaclyn W McAlees, Theresa Baker, Lauren Houshel, Christopher McKnight, Andrew Lindsley, Richard T Strait, Xue Zhang, Angela Cannata, Jocelyn M Biagini, Melinda Butsch Kovacic and 1 more

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Delayed Microbial Maturation Durably Exacerbates Th17-driven Asthma in Mice.American journal of respiratory cell and molecular biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jaclyn W McAleesDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Theresa BakerDivision of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Lauren HoushelDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Christopher McKnightDivision of Allergy, Immunology and Rheumatology, University of Cincinnati, Cincinnati, Ohio, USA.
Andrew LindsleyDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Richard T StraitDepartment of Emergency Medicine, Department of Pediatrics, Dayton Children's Hospital and Wright State University Boonshoft School of Medicine, Dayton, Ohio, USA.
Xue ZhangDepartment of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Angela CannataDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Jocelyn M BiaginiDivision of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Melinda Butsch KovacicDivision of Asthma Research, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Ian P LewkowichDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID 0000-0001-8133-3568
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · USWright State University · US

Funding

Mechanisms of IL-17A-mediated enhancement of asthma severityR01HL122300 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI LEWKOWICH, IAN PAUL · 2014 to 2018
$2.2M
Exposure-induced Systemic Oxidative Stress in Children with AsthmaR21ES016830 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI BUTSCHKOVACIC, MELINDA SUE · 2009 to 2010
$403k
NHLBI NIH HHS R01 HL122300NIEHS NIH HHS R21 ES016830
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Air PollutionAsthmaChildEpithelial CellsHumansInterleukin-17NeutrophilsInterleukin-17asthmaepithelial cellsIL-17Apaediatrics

Identifiers

PMID34908201
PMCPMC8976742
OpenAlexW4200254136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.