ArticleEndocrinology, diabetes & metabolism case reports2021
Subacute thyroiditis post-Pfizer-BioNTech mRNA vaccination for COVID-19.
Article in Endocrinology, diabetes & metabolism case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- SARS-CoV-2 vaccine-associated subacute thyroiditis: insights from a systematic review.Journal of endocrinological investigation · 2022Pooled it
- Thyroid Inconveniences With Vaccination Against SARS-CoV-2: The Size of the Matter. A Systematic Review.Frontiers in endocrinology · 2022Pooled it
- Vitamin D Modulates Humoral Responses to SARS-CoV-2 Vaccination in Autoimmune Thyroiditis: An Endocrine-Immune Perspective Supported by Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations.International journal of molecular sciences · 2026Article
- Risk of thyroid dysfunction after COVID-19 vaccination: meta-analysis of 11 million individuals.Annals of medicine and surgery (2012) · 2025Article
- ASIA Syndrome: State-of-the-Art and Future Perspectives.Vaccines · 2024Review
- Review
- Autoimmune/inflammatory syndrome induced by adjuvants (ASIA): past, present, and future implications.Clinical and experimental immunology · 2023Review
- COVID-19 vaccination and thyroiditis.Best practice & research. Clinical endocrinology & metabolism · 2023Review
- Insights into SARS-CoV-2-associated subacute thyroiditis: from infection to vaccine.Virology journal · 2023Review
- Article
- Increased incidence of Graves' disease during the SARS-CoV2 pandemic.Clinical endocrinology · 2023Observational
- Evaluation of metabolic changes in FDG PET/CT imaging after mRNA-based COVID-19 vaccination.Turkish journal of medical sciences · 2022Observational
- Thyroid dysfunction following vaccination with COVID-19 vaccines: a basic review of the preliminary evidence.Journal of endocrinological investigation · 2022Review
- Evaluation of the diagnostic features and clinical course of COVID-19 vaccine-associated subacute thyroiditis.Hormones (Athens, Greece) · 2022Article
- The New Entity of Subacute Thyroiditis amid the COVID-19 Pandemic: From Infection to Vaccine.Diagnostics (Basel, Switzerland) · 2022Review
- Two Case Reports of Subacute Thyroiditis after Receiving Vaccine for COVID-19.Case reports in endocrinology · 2022Article
- A Case of Hypophysitis Associated With SARS-CoV-2 Vaccination.AACE clinical case reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryThere is emerging evidence of an association between COVID-19 vaccination and subacute thyroiditis. We present the case of a 42-year-old female healthcare worker who was diagnosed with subacute thyroiditis 4 days after receiving her second dose of Pfizer-BioNTech vaccine. Her clinical course followed the classical pattern for thyroiditis with spontaneous return to euthyroidism at 6 months post-presentation. The autoimmune/inflammatory syndrome induced by adjuvants has been implicated as a cause of autoimmune conditions post-vaccination and is a potential mechanism for subacute thyroiditis in our case. LEARNING POINTS: Subacute thyroiditis should be considered in all patients who receive any kind of vaccine for COVID-19 and subsequently develop symptoms or signs of hyperthyroidism or neck pain. Subacute thyroiditis is a self-limiting condition, and recognising it is important as no specific thyroid treatment (antithyroid drugs or thyroid hormone replacement) is necessary for most patients. The autoimmune/inflammatory syndrome induced by adjuvants may be an under-recognised cause of endocrinopathies and should particularly be considered post-vaccination.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.