Evidence map›Paper›PMID 34907736›Full record

ReviewJournal of applied biomedicine2019

MR compatible ergometers for dynamic

Petr Sedivy, Monika Dezortova, Jan Rydlo, Miloslav Drobny, Martin Krssak, Ladislav Valkovic, Milan Hajek

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of applied biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. NMR in biomedicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Petr SedivyInstitute for Clinical and Experimental Medicine, Department of Diagnostic and Interventional Radiology, MR-unit, Prague, Czech Republic.
Monika DezortovaInstitute for Clinical and Experimental Medicine, Department of Diagnostic and Interventional Radiology, MR-unit, Prague, Czech Republic.
Jan RydloInstitute for Clinical and Experimental Medicine, Department of Diagnostic and Interventional Radiology, MR-unit, Prague, Czech Republic.
Miloslav DrobnyInstitute for Clinical and Experimental Medicine, Department of Diagnostic and Interventional Radiology, MR-unit, Prague, Czech Republic.
Martin KrssakMedical University of Vienna, Department of Internal Medicine III & High Field MR Centre, Division of Endocrinology and Metabolism, Department of Biomedical Imaging and Image guided Therapy, Vienna, Austria.
Ladislav ValkovicUniversity of Oxford, RDM Cardiovascular Medicine, Oxford Centre for Clinical MR Research (OCMR), Oxford, United Kingdom.
Milan HajekInstitute for Clinical and Experimental Medicine, Department of Diagnostic and Interventional Radiology, MR-unit, Prague, Czech Republic.

Funding

APVV 15-0029Ministry of Education, Youth and Sports 8J18AT023Ministry of Health of the Czech Republic AZV 15-26906AMinistry of Health of the Czech Republic MHCZ-DRO 00023001Royal Society 098436/Z/12/BSlovak Grant Agencies VEGA 2/0001/17
6 · The paper itself

Abstract

Magnetic Resonance (MR) compatible ergometers are specialized ergometers used inside the MR scanners for the characterization of tissue metabolism changes during physical stress. They are most commonly used for dynamic phosphorous magnetic resonance spectroscopy (31P MRS), but can also be used for lactate production measurements, perfusion studies using arterial spin labelling or muscle oxygenation measurements by blood oxygen dependent contrast sequences. We will primarily discuss the importance of ergometers in the context of dynamic 31P MRS. Dynamic 31P MRS can monitor muscle fatigue and energy reserve during muscle contractions as well as the dynamics of recuperation of skeletal muscle tissue during the following recovery through signal changes of phosphocreatine (PCr), inorganic phosphate and adenosine triphosphate (ATP). Based on the measured data it is possible to calculate intracellular pH, metabolic flux of ATP through creatine-kinase reaction, anaerobic glycolysis and oxidative phosphorylation and other metabolic parameters as mitochondrial capacity. This review primarily focuses on describing various technical designs of MR compatible ergometers for dynamic 31P MRS that must be constructed with respect to the presence of magnetic field. It is also expected that the construction of ergometers will be easy for the handling and well accepted by examined subjects.

Indexed as

Dynamic 31P magnetic resonance spectroscopyExerciseMR ergometerMuscle examination

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.