Evidence map›Paper›PMID 34907733›Full record

ArticleJournal of applied biomedicine2019

Versatile biomedical potential of biosynthesized silver nanoparticles from Acacia nilotica bark.

Geeta Arya, R Kumari, Richa Pundir, Sreemoyee Chatterjee, Nidhi Gupta, Ajeet Kumar, Ramesh Chandra, Surendra Nimesh

Abstract read
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In one paragraph

Article in Journal of applied biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Geeta AryaCentral University of Rajasthan, School of Life Sciences, Department of Biotechnology, Ajmer, Rajasthan, India.
R KumariCentral University of Rajasthan, School of Life Sciences, Department of Biotechnology, Ajmer, Rajasthan, India.
Richa PundirThe IIS University, Department of Biotechnology, Gurukul Marg, SFS, Mansarovar, Jaipur, Rajasthan, India.
Sreemoyee ChatterjeeThe IIS University, Department of Biotechnology, Gurukul Marg, SFS, Mansarovar, Jaipur, Rajasthan, India.
Nidhi GuptaThe IIS University, Department of Biotechnology, Gurukul Marg, SFS, Mansarovar, Jaipur, Rajasthan, India.
Ajeet KumarClarkson University, School of Arts and Sciences, Department of Chemistry and Biomolecular Science, Potsdam, New York, USA.
Ramesh ChandraUniversity of Delhi, Faculty of Science, Department of Chemistry, Delhi, India.
Surendra NimeshCentral University of Rajasthan, School of Life Sciences, Department of Biotechnology, Ajmer, Rajasthan, India.

Funding

Department of Biotechnology 6242-P82/RGCB/PMD/DBT/SNMH/2015
6 · The paper itself

Abstract

The present study reports the development of potent silver nanoparticles (AgNPs) using bark extract of Acacia nilotica and evaluation of its wound healing, anti-biofilm, anti-cancer and anti-microbial activity. Stable, small sized nanoparticles with spherical morphology were obtained after significant optimization studies that was evaluated through UV-visible spectroscopy. Thereafter, physicochemical characterization of biosynthesized AgNPs was carried out through DLS and FESEM for evaluation of size. EDAX and FTIR were carried out for the evaluation of composition and possible functional groups involved in the reduction and capping of AgNPs. The antibacterial potential was investigated through disc diffusion assay against Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa). Further, the Congo Red Assay (CRA) successfully revealed the anti-biofilm activity against Bacillus subtilis (B. subtilis), Staphylococcus aureus (S. aureus), Proteus vulgaris (P. vulgaris), Pseudomonas aeruginosa (P. aeruginosa). Alamar blue assay was conducted in A549 cells to reveal the remarkable anticancer activity of biosynthesized AgNPs that resulted in a very appreciable manner. Further, the wound healing activity of AgNPs can heal the excised wound of mice up-to 100% within 15 days. All these studies suggested that our biosynthesized AgNPs possess versatile biomedical application.

Indexed as

Acacia niloticaantibacterialantibiofilmanticancersilver nanoparticleswound healing

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.