Evidence map›Paper›PMID 34907289›Full record

ArticleScientific reports2021

In situ lymphoma imaging in a spontaneous mouse model using the Cerenkov Luminescence of F-18 and Ga-67 isotopes.

Zsombor Ritter, Katalin Zámbó, Péter Balogh, Dávid Szöllősi, Xinkai Jia, Ákos Balázs, Gabriella Taba, Dániel Dezső, Ildikó Horváth, Hussain Alizadeh and 7 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Zsombor RitterDepartment of Nuclear Medicine, Medical School, University of Pécs, Pécs, Hungary.
Katalin ZámbóDepartment of Nuclear Medicine, Medical School, University of Pécs, Pécs, Hungary.
Péter BaloghDepartment of Immunology and Biotechnology, University of Pécs, Pécs, Hungary.
Dávid SzöllősiDepartment of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary.
Xinkai JiaDepartment of Immunology and Biotechnology, University of Pécs, Pécs, Hungary.
Ákos BalázsSemmelweis University Faculty of Medicine 1st Department of Surgery, Budapest, Hungary.
Gabriella TabaSemmelweis University Dosimetry and Medical Physics Service, Budapest, Hungary.
Dániel DezsőDepartment of Nuclear Medicine, Medical School, University of Pécs, Pécs, Hungary.
Ildikó HorváthDepartment of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary.
Hussain Alizadeh1St Department of Internal Medicine, University of Pécs Medical School, Pécs, Hungary.
David TuchLightpoint Medical Ltd., Rickmansworth, UK.
Kunal VyasLightpoint Medical Ltd., Rickmansworth, UK.
Nikolett HegedűsDepartment of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary.
Tibor KovácsInstitute of Radiochemistry and Radioecology, University of Pannonia, Veszprém, Hungary.
Krisztián SzigetiDepartment of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary.
Domokos MáthéDepartment of Biophysics and Radiation Biology, Semmelweis University Faculty of Medicine, Budapest, Hungary. domokos.mathe@cromedresearch.com.
Erzsébet SchmidtDepartment of Nuclear Medicine, Medical School, University of Pécs, Pécs, Hungary.
University of Pecs · HUSemmelweis University · HULightpoint Medical (United Kingdom) · GBMontavid Thermodynamic Research Group · HUUniversity of Pannonia · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerenkov luminescence imaging (CLI) is a promising approach to image-guided surgery and pathological sampling. It could offer additional advantages when combined to whole-body isotope tomographies. We aimed to obtain evidence of its applicability in lymphoma patho-diagnostics, thus we decided to investigate the radiodiagnostic potential of combined PET or SPECT/CLI in an experimental, novel spontaneous high-grade B-cell lymphoma mouse model (Bc.DLFL1). We monitored the lymphoma dissemination at early stage, and at clinically relevant stages such as advanced stage and terminal stage with in vivo 2-deoxy-2-[

Indexed as

Luminescent MeasurementsPositron-Emission TomographyAnimalsFluorodeoxyglucose F18Gallium RadioisotopesLymphomaMiceMice, Inbred BALB CNeoplasms, ExperimentalFluorodeoxyglucose F18Gallium-67Gallium Radioisotopes

Identifiers

PMID34907289
PMCPMC8671545
OpenAlexW4225760214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.