Evidence map›Paper›PMID 34907255›Full record

ArticleScientific reports2021

Er:YAG laser irradiation enhances bacterial and lipopolysaccharide clearance and human gingival fibroblast adhesion on titanium discs.

Chen-Ying Wang, Bor-Shiunn Lee, Ya-Ting Jhang, Kevin Sheng-Kai Ma, Chen-Pang Huang, Kuan-Lun Fu, Chern-Hsiung Lai, Wan-Yu Tseng, Mark Yen-Ping Kuo, Yi-Wen Chen

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Photoinactivation and Photoablation ofPathogens (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chen-Ying Wang *Department of Dentistry, National Taiwan University Hospital, Taipei, Taiwan.
Bor-Shiunn Lee *Department of Dentistry, National Taiwan University Hospital, Taipei, Taiwan.
Ya-Ting JhangDepartment of Dentistry, National Taiwan University Hospital, Taipei, Taiwan.
Kevin Sheng-Kai MaGraduate Institute of Biomedical Electronics and Bioinformatics, College of Electrical Engineering and Computer Science, National Taiwan University, Taipei, Taiwan.
Chen-Pang HuangDepartment of Dentistry, National Taiwan University Hospital, Taipei, Taiwan.
Kuan-Lun FuDepartment of Dentistry, National Taiwan University Hospital, Taipei, Taiwan.
Chern-Hsiung LaiCollege of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
Wan-Yu TsengDepartment of Dentistry, National Taiwan University Hospital, Taipei, Taiwan.
Mark Yen-Ping KuoDepartment of Dentistry, National Taiwan University Hospital, Taipei, Taiwan.
Yi-Wen ChenDepartment of Dentistry, National Taiwan University Hospital, Taipei, Taiwan. yiwenchen@ntu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the effect of Er:YAG laser treatment on lipopolysaccharide (LPS) clearance and fibroblast adhesion on titanium disks. Grade IV titanium discs (n = 216) were used and allocated to 6 groups. Group 1 was the negative control without Porphyromonas gingivalis inoculation. Discs in Groups 2-6 were incubated with P. gingivalis to form a biofilm. Group 3 received 0.12% chlorhexidine irrigation and Group 4 received titanium curettage to remove the biofilm. Group 5 was treated with Er:YAG laser irradiation and Group 6 was treated with titanium curettage plus Er:YAG laser irradiation. The contact angle and surface roughness were measured after the various treatments. The surface microstructure and residual bacteria were examined using scanning electron microscopy and confocal laser scanning microscopy, respectively. Residual LPS was examined using a limulus amoebocyte lysate assay and human gingival fibroblast adhesion was quantified using fluorescent microscopy. Curettage plus Er:YAG laser irradiation was the most effective method for removing bacteria and LPS. No significant difference in the amount of fibroblast adhesion was found between the control and Group 6. Combined use of Er:YAG laser irradiation and curettage optimizes LPS clearance and fibroblast adhesion on titanium discs.

Indexed as

DisinfectionBiofilmsFibroblastsGingivaHumansLasers, Solid-StateLipopolysaccharidesMicroscopy, Electron, ScanningPorphyromonas gingivalisTitaniumLipopolysaccharidesTitanium

Identifiers

PMID34907255
PMCPMC8671504

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.