Evidence map›Paper›PMID 34907226›Full record

ArticleScientific reports2021

Emergency activations for chest pain and ventricular arrhythmias related to regional COVID-19 across the US.

Sidney Aung, Eric Vittinghoff, Gregory Nah, Anthony Lin, Sean Joyce, N Clay Mann, Gregory M Marcus

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Lack of temporal correlations between COVID pandemic waves and the occurrence of malignant ventricular arrhythmias.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  5. Article
  6. Effects of COVID-19 on STEMI Patients: Single-Center Experience.Heart views : the official journal of the Gulf Heart Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sidney AungDivision of Cardiology, University of California, 505 Parnassus Ave, M1180B, San Francisco, CA, 94143, USA.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Gregory NahDivision of Cardiology, University of California, 505 Parnassus Ave, M1180B, San Francisco, CA, 94143, USA.
Anthony LinDepartment of Medicine, University of California, San Francisco, USA.
Sean JoyceDivision of Cardiology, University of California, 505 Parnassus Ave, M1180B, San Francisco, CA, 94143, USA.
N Clay MannDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, USA.
Gregory M MarcusDivision of Cardiology, University of California, 505 Parnassus Ave, M1180B, San Francisco, CA, 94143, USA. greg.marcus@ucsf.edu.
University of California, San Francisco · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence that patients may avoid healthcare facilities for fear of COVID-19 infection has heightened the concern that true rates of myocardial infarctions have been under-ascertained and left untreated. We analyzed data from the National Emergency Medical Services Information System (NEMSIS) and incident COVID-19 infections across the United States (US) between January 1, 2020 and April 30, 2020. Grouping events by US Census Division, multivariable adjusted negative binomial regression models were utilized to estimate the relationship between COVID-19 and EMS cardiovascular activations. After multivariable adjustment, increasing COVID-19 rates were associated with less activations for chest pain and non-ST-elevation myocardial infarctions. Simultaneously, increasing COVID-19 rates were associated with more activations for cardiac arrests, ventricular fibrillation, and ventricular tachycardia. Although direct effects of COVID-19 infections may explain these discordant observations, these findings may also arise from patients delaying or avoiding care for myocardial infarction, leading to potentially lethal consequences.

Indexed as

Arrhythmias, CardiacChest PainCOVID-19HumansModels, TheoreticalNon-ST Elevated Myocardial InfarctionUnited States

Identifiers

PMID34907226
PMCPMC8671431
OpenAlexW4200456357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.