Evidence map›Paper›PMID 34907124›Full record

ReviewRetina (Philadelphia, Pa.)2022

MYTHS AND TRUTHS OF THE ASSOCIATION OF RETINAL VASCULAR OCCLUSION WITH COVID-19.

Ashish Sharma, Nikulaa Parachuri, Nilesh Kumar, Mario Rosario Romano, Barbara Parolini, Sengul Ozdek, Mohamed A Tawfik, Ameen Marashi, Baruch D Kuppermann, Quan Dong Nguyen

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Retina (Philadelphia, Pa.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Ashish SharmaLotus Eye Hospital and Institute, Coimbatore, Tamil Nadu, India.ORCID 0000-0002-8550-9791
Nikulaa ParachuriLotus Eye Hospital and Institute, Coimbatore, Tamil Nadu, India.
Nilesh KumarLotus Eye Hospital and Institute, Coimbatore, Tamil Nadu, India.
Mario Rosario RomanoDepartment of Biomedical Science, Humanitas University, Milan, Italy.
Barbara ParoliniEyecare Clinic, Brescia, Italy.
Sengul OzdekOphthalmology, Gazi University, School of Medicine, Ankara, Turkey.
Mohamed A TawfikMarashi Eye Clinic, Aleppo, Syria.
Ameen MarashiMemorial Institute of Ophthalmology Research, Cairo, Giza, Egypt.
Baruch D KuppermannGavin Herbert Eye Institute, University of California, Irvine, Irvine, California; and.
Quan Dong NguyenByers Eye Institute, Stanford University, Palo Alto, California.
Gazi University · TRHumanitas University · ITResearch Institute of Ophthalmology · EGSmith-Kettlewell Eye Research Institute · USUniversity of California, Irvine · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

purposeTo critically review data published in the recent past to scrutinize a causal relationship between retinal vascular occlusion and COVID-19.

methodA comprehensive literature search was performed on Pubmed with the key words retinal vascular occlusion, retinal vein occlusion, retinal artery occlusion, and COVID-19.

resultsA total of 17 case reports were published during this period, and 10 were on retinal vein occlusion and 7 on retinal artery occlusion. Most of the published reports lacked convincing evidences in one or the other aspects, such as insufficient laboratory workup or presence of multiple confounding risk factors.

conclusionIn this index article, strength of the data is insufficient to establish a definitive cause-and-effect relationship of retinal vascular occlusive disorders with COVID-19. Hence, clinicians can continue to manage these cases according to the standard guidelines until there are more robust evidences to support this association to alter the diagnostic and treatment modalities.

Indexed as

SARS-CoV-2AdolescentAdultAgedCOVID-19Eye Infections, ViralFemaleHumansMaleMiddle AgedMythologyRetinal Artery OcclusionRetinal Vein Occlusion

Identifiers

PMID34907124
PMCPMC10919546
OpenAlexW4200127408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.