Evidence map›Paper›PMID 34907099›Full record

ReviewAnnals of laboratory medicine2022

Myelodysplastic Syndromes with Bone Marrow Fibrosis: An Update.

Akriti G Jain, Ling Zhang, John M Bennett, Rami Komrokji

Open access · diamondAbstract readReview
In one paragraph

Review in Annals of laboratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Akriti G JainDepartment of Hematology and Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.ORCID https://orcid.org/0000-0002-7238-9241
Ling ZhangDepartment of Hematopathology and Laboratory Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.ORCID https://orcid.org/0000-0002-1463-1458
John M BennettHematopathology Division, Department of Pathology, University of Rochester Medical Center, Rochester, NY, USA.ORCID https://orcid.org/0000-0001-7517-5567
Rami KomrokjiDepartment of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.ORCID https://orcid.org/0000-0002-1876-5269
Moffitt Cancer Center · USUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelodysplastic syndrome (MDS) is a diverse hematological malignancy with a wide spectrum of presentations and implications. Treatment strategies for patients with MDS heavily rely on prognostic scoring systems, such as the revised international prognostic scoring system (IPSS-R). Bone marrow fibrosis (BMF) has been identified as an independent risk factor for poor survival in patients with MDS, irrespective of the IPSS-R risk category. However, BMF is not widely included in scoring systems and is not always considered by clinicians when making treatment decisions for patients. In this review, we discuss the available literature about the presentation and prognosis of patients with MDS and concurrent BMF. The prognostic impact of BMF should be factored in when deciding on transplant candidacy, especially for intermediate-risk patients.

Indexed as

Myelodysplastic SyndromesPrimary MyelofibrosisHumansPrognosisRisk FactorsAllogeneic stem cell transplantationBone marrow fibrosisInternational prognostic scoring systemMyelodysplastic syndrome

Identifiers

PMID34907099
PMCPMC8677477
OpenAlexW4200003368

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.