Evidence map›Paper›PMID 34906826›Full record

ArticleJournal of behavior therapy and experimental psychiatry2022

Association between spatial working memory and Re-experiencing symptoms in PTSD.

Abel S Mathew, Salahadin Lotfi, Kenneth P Bennett, Sadie E Larsen, Caron Dean, Christine L Larson, Han-Joo Lee

Open access · greenAbstract read
In one paragraph

Article in Journal of behavior therapy and experimental psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Memory in Psychiatric Disorders: A Review.Life (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Abel S MathewDepartment of Psychology, University of Wisconsin-Milwaukee, USA.
Salahadin LotfiDepartment of Psychology, University of Wisconsin-Milwaukee, USA; Rogers Behavioral Health, Research Center and Clinical Effectiveness Department, USA.
Kenneth P BennettDepartment of Psychology, University of Wisconsin-Milwaukee, USA.
Sadie E LarsenMilwaukee VA Medical Center, USA; Medical College of Wisconsin, USA.
Caron DeanMilwaukee VA Medical Center, USA; Medical College of Wisconsin, USA.
Christine L LarsonDepartment of Psychology, University of Wisconsin-Milwaukee, USA.
Han-Joo LeeDepartment of Psychology, University of Wisconsin-Milwaukee, USA. Electronic address: leehj@uwm.edu.
University of Wisconsin–Milwaukee · USMedical College of Wisconsin · USRogers Behavioral Health · US

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
NCATS NIH HHS UL1 TR001436
6 · The paper itself

Abstract

BACKGROUND AND

objectivesFew studies have evaluated the link between working memory (WM) and post-traumatic stress disorder (PTSD). Further, it is unknown whether this relationship is accounted for by other relevant variables including negative affect, emotional dysregulation, or general non-WM-related cognitive control deficits, which are associated with PTSD. The purpose of this study was to determine the extent to which a computerized WM task could predict PTSD symptomology incrementally beyond the contribution of other relevant variables associated with PTSD.

methodsThirty veterans were eligible to complete emotional symptom questionnaires, a heart-rate variability measure, and computerized tasks (i.e., emotional Stroop and automated complex span tasks). A three-stage hierarchical regression was conducted with the PCL-5 total score and symptom clusters (i.e., re-experiencing, avoidance, hyperarousal, and negative cognition/mood) as the dependent variable.

resultsResults revealed that only the re-experiencing symptom cluster was significantly predicted by executive, verbal, and visuospatial WM tasks, which explained an additional 29.7% of the variance over and above other relevant variables. Most notably, the visuospatial task was the only WM task that significantly explained PCL-5 re-experiencing symptoms. LIMITATIONS: This study was based on a small sample of veterans with PTSD and causality cannot be determined with this cross-sectional study.

conclusionsOverall, the results suggest that deficits in visuospatial WM are significantly associated with PTSD re-experiencing symptoms after controlling for other relevant variables. Further research should evaluate whether an intervention to improve visuospatial WM capacity can be implemented to reduce re-experiencing symptoms.

Indexed as

Stress Disorders, Post-TraumaticVeteransCross-Sectional StudiesEmotionsHumansMemory, Short-TermPTSDRe-experiencing symptomsVisuospatial WMWorking Memory

Identifiers

PMID34906826
PMCPMC9173718
OpenAlexW4200098215

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.