Evidence map›Paper›PMID 34906799›Full record

ArticleSeizure2022

Epilepsy is overrepresented among young people who died from COVID-19: Analysis of nationwide mortality data in Hungary.

Réka A Horváth, Zsófia Sütő, Balázs Cséke, Dániel Schranz, Gergely Darnai, Norbert Kovács, Imre Janszky, József Janszky

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In one paragraph

Article in Seizure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Réka A HorváthDepartment of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary. Electronic address: horvath.reka@pte.hu.
Zsófia SütőDepartment of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary. Electronic address: suto.zsofia@pte.hu.
Balázs CsékeDepartment of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary. Electronic address: cseke.balazs@pte.hu.
Dániel SchranzDepartment of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary. Electronic address: schranz.daniel@pte.hu.
Gergely DarnaiDepartment of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary; MTA-PTE Clinical Neuroscience MRI Research Group. Hungary, Ifjúság u. 20., H-7624 Pécs, Hungary; Department of Behavioral Sciences, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary. Electronic address: darnai.gergely@pte.hu.
Norbert KovácsDepartment of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary; MTA-PTE Clinical Neuroscience MRI Research Group. Hungary, Ifjúság u. 20., H-7624 Pécs, Hungary. Electronic address: kovacs.norbert@pte.hu.
Imre JanszkyDepartment of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Håkon Jarls gate 11 and Mauritz Hanssens gate, 7491 Trondheim, Norway; Regional Center for Health Care Improvement, St Olav's Hospital, Trondheim, Norway. Electronic address: imre.janszky@ntnu.no.
József JanszkyDepartment of Neurology, Medical School, University of Pécs, Rét u. 2, H-7623 Pécs, Hungary; MTA-PTE Clinical Neuroscience MRI Research Group. Hungary, Ifjúság u. 20., H-7624 Pécs, Hungary. Electronic address: janszky.jozsef@pte.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies examining epilepsy as a COVID-related death risk have come to conflicting conclusions. Our aim was to assess the prevalence of epilepsy among COVID-related deaths in Hungary.

methodsEach COVID-19 infection case is required to be reported on a daily basis to the National Public Health Center of Hungary. This online report includes the beginning and end of the infection, as well as information on comorbidities. Death during infection is regarded as COVID-related. The anonymized data of each deceased patient are published on an information website (www.koronavirus.gov.hu) and provides up-to-date information on each patient with the date of death, the patient's sex, age, and chronic illness.

resultsThere were 11,968 patients who died of COVID-19 in Hungary between 13 March 2020 and 23 January 2021. Among 11,686 patients with no missing values for comorbidities, 255 patients had epilepsy (2.2%). Epilepsy was much more common among those who died at a young age: 9.3% of those who died under the age of 50 had epilepsy, compared with only 1.3% in those over the age of 80. The younger an age group was, the higher was the prevalence of epilepsy.

conclusionPatients who died of COVID-19 under the age of 50 were 10 to 20 times more likely to have epilepsy than what would have been expected from epidemiological data. Our results highlight the need for increased protection of young people with epilepsy from COVID-19 infection and the development of a vaccination strategy accordingly.

Indexed as

COVID-19EpilepsyAdolescentChildHumansHungaryPrevalenceSARS-CoV-2AgeCOVID-19DeathEpilepsyHungaryIntellectual disability

Identifiers

PMID34906799
PMCPMC8634695

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.