Evidence map›Paper›PMID 34906715›Full record

ArticleNeuroImage2022

Connectomics of human electrophysiology.

Sepideh Sadaghiani, Matthew J Brookes, Sylvain Baillet

Abstract read
In one paragraph

Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Tracking electrophysiological signatures of Alzheimer's disease: a systematic review of multimodal studies.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sepideh SadaghianiDepartment of Psychology, University of Illinois, Urbana-Champaign, IL, United States; Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign, IL, United States.
Matthew J BrookesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG72RD, United Kingdom.
Sylvain BailletMcConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.

Funding

BrainStorm: Highly Extensible Software for Advanced Electrophysiology and MEG/EEG ImagingR01EB026299 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LEAHY, RICHARD M · 2018 to 2025
$5.4M
Cognitive Significance of Functional Connectome StatesR01MH116226 · NIMH · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SADAGHIANI, SEPIDEH · 2019 to 2023
$2.3M
NIBIB NIH HHS R01 EB026299NIMH NIH HHS R01 MH116226
6 · The paper itself

Abstract

We present both a scientific overview and conceptual positions concerning the challenges and assets of electrophysiological measurements in the search for the nature and functions of the human connectome. We discuss how the field has been inspired by findings and approaches from functional magnetic resonance imaging (fMRI) and informed by a small number of significant multimodal empirical studies, which show that the canonical networks that are commonplace in fMRI are in fact rooted in electrophysiological processes. This review is also an opportunity to produce a brief, up-to-date critical survey of current data modalities and analytical methods available for deriving both static and dynamic connectomes from electrophysiology. We review hurdles that challenge the significance and impact of current electrophysiology connectome research. We then encourage the field to take a leap of faith and embrace the wealth of electrophysiological signals, despite their apparent, disconcerting complexity. Our position is that electrophysiology connectomics is poised to inform testable mechanistic models of information integration in hierarchical brain networks, constructed from observable oscillatory and aperiodic signal components and their polyrhythmic interactions.

Indexed as

Electrophysiological PhenomenaBrainConnectomeElectrophysiologyHumansMagnetic Resonance ImagingNerve Net

Identifiers

PMID34906715
PMCPMC8943906

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.