ArticleNeuron2022
Learning and attention increase visual response selectivity through distinct mechanisms.
Article in Neuron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Retrosplenial cortex enables context-dependent goal-directed sensorimotor transformation.eLife · 2026Article
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- Rapid dynamics of dorsal raphe serotonin neurons regulate the strength of visual attention.Nature communications · 2026Article
- Open-Source Platform for Adjustable Training Regimes in Freely Moving and Head-Fixed Mice.eNeuro · 2026Article
- Neuronal Features of Visual Attention in the Mouse Superior Colliculus Depend on Learned Behavioral Relevance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Occipital and parietal non-invasive brain stimulation enhances perceptual learning and transfer: evidence from high-frequency tRNS.Frontiers in neuroscience · 2026Article
- Neuronal signatures of successful one-shot memory in mid-level visual cortex.bioRxiv : the preprint server for biology · 2025Article
- Long-lasting, subtype-specific regulation of somatostatin interneurons during sensory learning.Science advances · 2025Article
- Feature-specific inhibitory connectivity augments the accuracy of cortical representations.bioRxiv : the preprint server for biology · 2025Article
- Learning, prediction accuracy, and neural plasticity in sensory cortex.Current opinion in neurobiology · 2025Review
- Context flexibly modulates cue representations in visual cortex.Nature communications · 2025Article
- Untangling stability and gain modulation in cortical circuits with multiple interneuron classes.eLife · 2025Article
- Integrating multimodal data to understand cortical circuit architecture and function.Nature neuroscience · 2025Review
- Neocortical somatostatin neuron diversity in cognition and learning.Trends in neurosciences · 2025Review
- Simultaneous interneuron labeling reveals cell type-specific, population-level interactions in cortex.iScience · 2024Article
- Prediction-error signals in anterior cingulate cortex drive task-switching.Nature communications · 2024Article
- Recurrent inhibition refines mental templates to optimize perceptual decisions.Science advances · 2024Article
- Flexible neural population dynamics govern the speed and stability of sensory encoding in mouse visual cortex.Nature communications · 2024Article
- A transthalamic pathway crucial for perception.Nature communications · 2024Article
- Anterior cingulate cortex provides the neural substrates for feedback-driven iteration of decision and value representation.Nature communications · 2024Article
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9 authors.
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Abstract
Selectivity of cortical neurons for sensory stimuli can increase across days as animals learn their behavioral relevance and across seconds when animals switch attention. While both phenomena occur in the same circuit, it is unknown whether they rely on similar mechanisms. We imaged primary visual cortex as mice learned a visual discrimination task and subsequently performed an attention switching task. Selectivity changes due to learning and attention were uncorrelated in individual neurons. Selectivity increases after learning mainly arose from selective suppression of responses to one of the stimuli but from selective enhancement and suppression during attention. Learning and attention differentially affected interactions between excitatory and PV, SOM, and VIP inhibitory cells. Circuit modeling revealed that cell class-specific top-down inputs best explained attentional modulation, while reorganization of local functional connectivity accounted for learning-related changes. Thus, distinct mechanisms underlie increased discriminability of relevant sensory stimuli across longer and shorter timescales.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.