Evidence map›Paper›PMID 34906165›Full record

ArticleReproductive biology and endocrinology : RB&E2021

Increased METTL3-mediated m

Pingping Xue, Wenbo Zhou, Wenqiang Fan, Jianya Jiang, Chengcai Kong, Wei Zhou, Jianmei Zhou, Xiaoyang Huang, Haiyan Yang, Qian Han and 4 more

Open access · goldAbstract read
In one paragraph

Article in Reproductive biology and endocrinology : RB&E, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. The role of mGenes & diseases · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. METTL3 is essential for normal progesterone signaling during embryo implantation via mProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Pingping Xue *Department of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Wenbo Zhou *Department of Medical Genetics, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Wenqiang Fan *Department of Mammary Surgery, Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Jianya JiangDepartment of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Chengcai KongDepartment of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Wei ZhouDepartment of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Jianmei ZhouDepartment of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Xiaoyang HuangDepartment of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Haiyan YangDepartment of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Qian HanDepartment of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Bin ZhangDepartment of Medical Genetics, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China.
Lingyun XuDepartment of Mammary Surgery, Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China. mengxi4648@163.com.
Bin YuDepartment of Medical Genetics, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China. binyu@njmu.edu.cn.
Li ChenDepartment of Reproductive Medicine Center, Changzhou Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Changzhou, 213000, China. czrcchenli@126.com.
Nanjing Medical University · CNNanjing Maternity and Child Health Care Hospital · CNChangzhou No.2 People's Hospital · CN

Funding

great science and technology project of changzhou municipal health commission ZD201921great science and technology project of changzhou municipal health commission ZD202016natural science foundation of jiangsu province BK20201158qingmiao talents training program of changzhou health commission CZQM2020095qingmiao talents training program of changzhou health commission CZQM2020103
6 · The paper itself

Abstract

backgroundRecurrent implantation failure (RIF) is a major limitation of assisted reproductive technology, which is associated with impaired endometrial receptivity. Although N

methodsGlobal m

resultsGlobal m

conclusionIncreased METTL3-mediated m

Indexed as

AdultCell Line, TumorDNA MethylationEmbryo ImplantationEndometriumFemaleHomeobox A10 ProteinsHumansInfertility, FemaleMethyltransferasesHomeobox A10 ProteinsHOXA10 protein, humanMethyltransferasesMETTL3 protein, humanembryo implantationHOXA10m6A methylationMETTL3recurrent implantation failure

Identifiers

PMID34906165
PMCPMC8670269
OpenAlexW4200444390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.