Evidence map›Paper›PMID 34906107›Full record

ArticleBMC surgery2021

The value of multimodal ultrasonography in differential diagnosis of tuberculous and non-tuberculous superficial lymphadenitis.

Jie Chu, Ying Zhang, Wenzhi Zhang, Dan Zhao, Jianping Xu, Tianzhuo Yu, Gaoyi Yang

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jie ChuDepartment of Ultrasound, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, 208 Huancheng East Road, Downtown District, Hangzhou, 310003, Zhejiang, China.
Ying ZhangDepartment of Ultrasound, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, 208 Huancheng East Road, Downtown District, Hangzhou, 310003, Zhejiang, China.
Wenzhi ZhangDepartment of Ultrasound, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, 208 Huancheng East Road, Downtown District, Hangzhou, 310003, Zhejiang, China.
Dan ZhaoDepartment of Ultrasound, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, 208 Huancheng East Road, Downtown District, Hangzhou, 310003, Zhejiang, China.
Jianping XuDepartment of Ultrasound, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, 208 Huancheng East Road, Downtown District, Hangzhou, 310003, Zhejiang, China.
Tianzhuo YuDepartment of Ultrasound, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, 208 Huancheng East Road, Downtown District, Hangzhou, 310003, Zhejiang, China.
Gaoyi YangDepartment of Ultrasound, Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine, 208 Huancheng East Road, Downtown District, Hangzhou, 310003, Zhejiang, China. yanggaoyi@163.com.
Zhejiang Hospital · CN

Funding

Agriculture and Social development plan 20190101A09Medical Science and Technology Project of Zhejiang Province 2019KY513the Science and Technology plan of Hangzhou 20180533B68
6 · The paper itself

Abstract

backgroundTo investigate the value of multimodal ultrasonography in differentiating tuberculosis from other lymphadenopathy.

methodsSixty consecutive patients with superficial lymphadenopathy treated at our hospital from January 2017 to December 2018 were categorized into four types based on the color Doppler ultrasound, five types based on contrast-enhanced ultrasound, and five types based on elastography. Sensitivity and specificity were calculated of all the three imaging, including color Doppler examination, contrast-enhanced ultrasound and one individual multimodal method, for detecting lymph nodes.

resultsA total of 60 patients were included in the final analysis. Of those, Mycobacterium tuberculosis was positive in 38 patients and negative in 22 patients. Among the 38 patients who were positive for Mycobacterium tuberculosis, of which 23 had a history of pulmonary tuberculosis, accounting for 60.53% of the positive cases, and the remaining patients did not combine lesions of other organs. Among the 60 superficial lymph nodes, 63.3% presented with tuberculous lymphadenitis. The sensitivity, specificity, and accuracy of the color Doppler examination were 73.68%, 68.18%, and 71.67%, respectively. The sensitivity, specificity and accuracy of contrast-enhanced ultrasound were 89.47%, 63.64% and 80.00%, respectively. The sensitivity, specificity and accuracy of the elastography were 63.16%, 63.64% and 63.33%, respectively. The sensitivity, specificity and accuracy of one individual multimodal method were 42.11%, 95.45% and 61.67%, respectively. The sensitivity, specificity and accuracy of all modes combined were 100.00%, 27.27% and 73.33%, respectively.

conclusionMultimodal ultrasonography has high predictive value for the differential diagnosis of superficial tuberculous lymphadenitis.

Indexed as

LymphadenitisLymphadenopathyTuberculosis, Lymph NodeDiagnosis, DifferentialHumansLymph NodesUltrasonographyMultimodal ultrasonographySuperficial tuberculous lymphadenitisTuberculosis

Identifiers

PMID34906107
PMCPMC8670034
OpenAlexW4200358347

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.