Evidence map›Paper›PMID 34906070›Full record

ArticleBMC infectious diseases2021

The first case of Ochrobactrum intermedium bacteremia in a pediatric patient with malignant tumor.

Wenjing Wu, Yongmei Jiang, Wei Zhou, Xingxin Liu, Linghan Kuang

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wenjing WuDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.
Yongmei JiangDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.
Wei ZhouDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.
Xingxin LiuDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.
Linghan KuangDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China. hanhan840106@163.com.
West China Second University Hospital of Sichuan University · CNSichuan University · CN

Funding

Department of Science and Technology of Sichuan Province 20ZDYF3310National Natural Science Foundation of China 32070747Science and Technology Bureau of Chengdu 2019-YF05-01178-SNthe Key R&D project of Science & technology Department of Sichuan Province 2020YFS0081the Popularization and Application project of Health Commission of Sichuan Province 19PJ070
6 · The paper itself

Abstract

backgroundOchrobactrum spp. are non-fermenting, Gram-negative bacilli that are regarded as emerging human pathogens of low virulence that can cause infections. The first identified case of Ochrobactrum intermedium was reported in 1998 in a liver transplantation patient with liver abcess. There are no reports of infections in pediatric patients. Here, we report the first case of O. intermedium bacteremia in a pediatric patient. CASE PRESENTATION: A two and a half years old male was admitted with fever, chills and nausea. He had been diagnosed as pineoblastoma and underwent surgical resection and chemotherapy. O. intermedium was isolated from his blood cultures and identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), however, the Vitek II automated system failed to identify the organism. Then the pathogen was confirmed by 16S rDNA sequencing and average nucleotide identity result (ANI) confirmed the precise identification of O. intermedium at genomic level. In addition, the patient recovered well after antibiotic combined therapy.

conclusionsThis, to our knowledge, is the first case of O. intermedium bacteremia in a pediatric patient with malignant tumor. Traditional biochemical identification methods such as API 20NE or VITEK2 system cannot differentiate O. anthropi and O. intermedium. MALDI-TOF may be a promising tool for rapid identification of microorganisms such as O. intermedium.

Indexed as

BacteremiaGram-Negative Bacterial InfectionsNeoplasmsOchrobactrumChild, PreschoolHumansMaleBacteremiaOchrobactrumOchrobactrum intermediumPediatric patient

Identifiers

PMID34906070
PMCPMC8670145
OpenAlexW4200085920

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.