Evidence map›Paper›PMID 34905644›Full record

ArticleMaternal & child nutrition2022

A nation-wide study on the common reasons for infant formula supplementation among healthy, term, breastfed infants in US hospitals.

Larelle H Bookhart, Erica H Anstey, Michael R Kramer, Cria G Perrine, Harumi Reis-Reilly, Usha Ramakrishnan, Melissa F Young

Open access · goldAbstract read
In one paragraph

Article in Maternal & child nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Beyond first sip: combination of intermittent cow's milk exposure and atopic dermatitis associated with severe IgE mediated cow's milk reactions-a retrospective study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Association Between Breastfeeding Intensity and Mammary Gland Involution Markers in Early Postpartum Among Women from Low-Income Households.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. "Breast is best"… until they say so.Frontiers in sociology · 2023
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Larelle H BookhartHubert Department of Global Health, Doctoral Program in Nutrition and Health Sciences, Laney Graduate School, Emory University, Atlanta, Georgia, USA.ORCID 0000-0003-2315-9295
Erica H AnsteyDivision of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Michael R KramerDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Cria G PerrineDivision of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Harumi Reis-ReillyMaternal and Child Health, National Association of County and City Health Officials, Washington, District of Columbia, USA.
Usha RamakrishnanHubert Department of Global Health, Doctoral Program in Nutrition and Health Sciences, Laney Graduate School, Emory University, Atlanta, Georgia, USA.
Melissa F YoungHubert Department of Global Health, Doctoral Program in Nutrition and Health Sciences, Laney Graduate School, Emory University, Atlanta, Georgia, USA.
Emory University · USCenters for Disease Control and Prevention · USNational Association of County and City Health Officials · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In-hospital infant formula supplementation of breastfed infants reduces breastfeeding duration, yet little is known about common reasons for infant formula supplementation. We examined the three most common reasons for in-hospital infant formula supplementation of healthy, term, breastfed infants in the US reported by hospital staff. Hospital data were obtained from the 2018 Maternity Practices in Infant Nutrition and Care survey (n = 2045), which is completed by hospital staff. An open-ended question on the top three reasons for in-hospital infant formula supplementation was analyzed using thematic qualitative analysis and the frequencies for each reason were reported. The top three most common reasons for in-hospital infant formula supplementation reported by hospital staff included medical indications (70.0%); maternal request/preference/feelings (55.9%); lactation management-related issues (51.3%); physical but non-medically indicated reasons (36.1%); social influences (18.8%); perceived cultural/societal/demographic factors (8.2%) and medical staff/institutional practices (4.7%). These findings suggest that a variety of factors should be considered to address unnecessary infant formula supplementation. Lactation management support delivered in a timely and culturally sensitive manner and targeted to mother-infant dyads with potential medical and physical indications may reduce unnecessary in-hospital infant formula supplementation.

Indexed as

Breast FeedingInfant FormulaDietary SupplementsFemaleHospitalsHumansInfantInfant Nutritional Physiological PhenomenaPregnancybreastfeedingbreastfeeding initiationbreast milk substitutesdeveloped countriesinfant formulaqualitative methods

Identifiers

PMID34905644
PMCPMC8932686
OpenAlexW4200020467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.