Evidence map›Paper›PMID 34905405›Full record

ArticleJCO oncology practice2022

Use of Communication Technology to Improve Clinical Trial Participation in Adolescents and Young Adults With Cancer: Consensus Statement From the Children's Oncology Group Adolescent and Young Adult Responsible Investigator Network.

Viswatej Avutu, Varun Monga, Nupur Mittal, Aniket Saha, Jeffrey R Andolina, Danielle E Bell, Douglas B Fair, Jamie E Flerlage, Jamie N Frediani, Jessica L Heath and 6 more

Abstract readConsensus Statement
In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Identifying caregiver-reported modifiable barriers to pediatric oncology clinical trial enrollment and participation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Challenges to successful outcomes in AYAs with ALL and potential solutions.Hematology. American Society of Hematology. Education Program · 2023
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Viswatej AvutuDepartment of Medicine, Memorial Sloan Kettering Cancer Center; New York, NY.ORCID 0000-0002-2591-7187
Varun MongaDivision of Medical Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA.ORCID 0000-0002-1185-5448
Nupur MittalDivision of Pediatric Hematology Oncology, Department of Pediatrics, Rush University Medical Center, Chicago, IL.ORCID 0000-0002-9622-7757
Aniket SahaDivision of Pediatric Hematology-Oncology, University of South Carolina School of Medicine, Greenville, SC.ORCID 0000-0002-1280-436X
Jeffrey R AndolinaDepartment of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, NY.ORCID 0000-0001-6502-6859
Danielle E BellDepartment of Pediatrics, Ascension St John Hospital, Detroit, MI.
Douglas B FairDivision of Hematology/Oncology, Department of Pediatrics, University of Utah, Primary Children's Hospital, Huntsman Cancer Institute, Salt Lake City, UT.
Jamie E FlerlageDepartment of Oncology, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-4182-9355
Jamie N FredianiDepartment of Pediatrics, University of California, Irvine, CA.
Jessica L HeathDepartments of Pediatrics and Biochemistry, University of Vermont, Burlington, VT.ORCID 0000-0003-1771-2242
Justine M KahnDivision of Pediatric Hematology/Oncology/Stem Cell Transplantation, Columbia University Irving Medical Center, New York, NY.ORCID 0000-0003-3330-6754
Jennifer L ReichekDivision of Hematology/Oncology/Stem Cell Transplantation, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Leanne SuperDepartment of Paediatrics, School of Medicine, Monash University, Melbourne, Australia.
Michael A TeraoDivision of Pediatric Adolescent and Young Adult Hematology and Oncology, Department of Pediatrics, Medstar Georgetown University Hospital, Washington, DC.ORCID 0000-0002-3018-4256
David R FreyerDepartments of Pediatrics, Medicine, and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.ORCID 0000-0001-5280-990X
Michael E RothDivision of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX.ORCID 0000-0002-6411-8353

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
NCI NIH HHS U10 CA180886
6 · The paper itself

Abstract

Adolescents and young adults (AYAs; age 15-39 years) with cancer are under-represented in cancer clinical trials because of patient, provider, and institutional barriers. Health care technology is increasingly available to and highly used among AYAs and has the potential to improve cancer care delivery. The COVID-19 pandemic forced institutions to rapidly adopt novel approaches for enrollment and monitoring of patients on cancer clinical trials, many of which have the potential for improving AYA trial participation overall. This consensus statement from the Children's Oncology Group AYA Oncology Discipline Committee reviews opportunities to use technology to optimize AYA trial enrollment and study conduct, as well as considerations for widespread implementation of these practices. The use of remote patient eligibility screening, electronic informed consent, virtual tumor boards, remote study visits, and remote patient monitoring are recommended to increase AYA access to trials and decrease the burden of participation. Widespread adoption of these strategies will require new policies focusing on reimbursement for telehealth, license portability, facile communication between electronic health record systems and advanced safeguards to maintain patient privacy and security. Studies are needed to determine optimal approaches to further incorporate technology at every stage of the clinical trial process, from enrollment through study completion.

Indexed as

COVID-19NeoplasmsAdolescentAdultChildCommunicationHumansPandemicsSARS-CoV-2TechnologyYoung Adult

Identifiers

PMID34905405
PMCPMC8932547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.