Trial reportHernia : the journal of hernias and abdominal wall surgery2022
Long-term follow-up of full-thickness skin grafting in giant incisional hernia repair: a randomised controlled trial.
Trial report in Hernia : the journal of hernias and abdominal wall surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01413412 (Full-thickness Skin vs. Synthetic Mesh in the Repair of Large Incisional Hernia - a Prospective Randomized Controlled Study), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Full-thickness Skin vs. Synthetic Mesh in the Repair of Large Incisional Hernia - a Prospective Randomized Controlled Study
Who cites it
11 citing papers in PubMed.
- Concurrent validity and agreement of the HerniaCare Lab device for abdominal wall strength assessment.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- A scoping review of outcome reporting in randomized controlled trials of incisional and non-incisional ventral hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Burn patients' perceptions of skin grafting in China: a single-center retrospective cohort study with paired pre-post assessment.Frontiers in public health · 2026Article
- A Case of Urothelial Carcinoma With Squamous Differentiation of the Bladder, Infiltrating the Small Intestine and Rectus Abdominis, Treated With the Use of a Short Gracilis Myocutaneous Flap.IJU case reports · 2025Article
- Complex abdomen: a scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Comparison of mechanical properties and host tissue response to OviTex™ and Strattice™ surgical meshes.Hernia : the journal of hernias and abdominal wall surgery · 2023Article
- Article
- Hernia repair using autografts.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Could full thickness skin grafts in an onlay position be the new gold standard for incisional hernia repair?Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Could full thickness skin grafts in an onlay position be the new gold standard for incisional hernia repair? Author's reply.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Reconstruction of Large Full-Thickness Abdominal Wall Defects Using a Free Functional Latissimus Dorsi Muscle.Frontiers in surgery · 2022Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeConventional repair of a giant incisional hernia often requires implantation of a synthetic mesh (SM). However, this surgical procedure can lead to discomfort, pain, and potentially serious complications. Full-thickness skin grafting (FTSG) could offer an alternative to SM, less prone to complications related to implantation of a foreign body in the abdominal wall. The aim of this study was to compare the use of FTSG to conventional SM in the repair of giant incisional hernia.
methodsPatients with a giant incisional hernia (> 10 cm width) were randomised to repair with either FTSG or SM. 3-month and 1-year follow-ups have already been reported. A clinical follow-up was performed 3 years after repair, assessing potential complications and recurrence. SF-36, EQ-5D and VHPQ questionnaires were answered at 3 years and an average of 9 years (long-term follow-up) after surgery to assess the impact of the intervention on quality-of-life (QoL).
resultsFifty-two patients were included. Five recurrences in the FTSG group and three in the SM group were noted at the clinical follow-up 3 years after surgery, but the difference was not significant (p = 0.313). No new procedure-related complication had occurred since the one-year follow-up. There were no relevant differences in QoL between the groups. However, there were significant improvemnts in both physical, emotional, and mental domains of the SF-36 questionnaire in both groups.
conclusionThe results of this long-term follow-up together with the results from previous follow-ups indicate that autologous FTSG as reinforcement in giant incisional hernia repair is an alternative to conventional repair with SM.
trial registrationThe study was registered August 10, 2011 at ClinicalTrials.gov (ID NCT01413412), retrospectively registered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.