Evidence map›Paper›PMID 34904796›Full record

ArticleBrain and behavior2022

Long-term effects of adolescent sport experience, DRD2 and COMT genes, and their interaction on sport participation in adulthood.

Chung Gun Lee, Hyoyoul Moon, Joon-Ho Kang, Joo Hee Choi, Ju Hyuk Kwon

Abstract read
In one paragraph

Article in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Chung Gun LeeDepartment of Physical Education, College of Education, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, South Korea.
Hyoyoul MoonDepartment of Physical Education, College of Education, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, South Korea.
Joon-Ho KangDepartment of Physical Education, College of Education, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, South Korea.
Joo Hee ChoiInstitute of Sport Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, South Korea.
Ju Hyuk KwonInstitute of Sport Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study investigated the joint impact of adolescent sport experience and dopamine-related genes (i.e., DRD2 and COMT genes) on sport participation in adulthood.

methodsUsing the National Longitudinal Study of Adolescent Health (Add Health) data, the hierarchical multivariable logistic regression models for predicting sport participation in wave 3 (around 20 years of age) and wave 4 (around 30 years of age) were conducted separately by gender (male and female) and gene (DRD2 and COMT genes).

resultsAdolescent sport experience significantly interacted with the number of DRD2 A1 alleles and COMT Met alleles in affecting wave 3 sport participation among male adults. The interaction between adolescent sport experience and DRD2 gene significantly affected wave 4 sport participation in opposite direction to that affected wave 3 sport participation among male participants. Among female participants, there were no significant interaction effects between dopamine-related genes and adolescent sport experience on sport participation in both wave 3 and 4.

conclusionsSince adult sport participation is most likely to be influenced by the joint impact of environmental and genetic factors, it is important to consider gene-by-environment interactions when designing policies or programs to promote adult sport participation.

Indexed as

Catechol O-MethyltransferaseReceptors, Dopamine D2SportsYouth SportsAdolescentAdultAllelesFemaleHumansLongitudinal StudiesMaleCatechol O-MethyltransferaseCOMT protein, humanDRD2 protein, humanReceptors, Dopamine D2adolescent sport experienceadulthoodCOMTDRD2gene-by environment interactionssport participation

Identifiers

PMID34904796
PMCPMC8785622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.