Evidence map›Paper›PMID 34904696›Full record

ArticleJournal of opioid management

Guideline adherence and reasons for recommending dose reduction in a primary care-based opioid management clinic.

Laila Khalid, Serena Roth, Chenshu Zhang, Aaron Burkenroad, Gianni Carrozzi, Joanna L Starrels

Open access · greenAbstract read
In one paragraph

Article in Journal of opioid management. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Laila KhalidMontefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York. ORCID: https://orcid.org/0000-0002-0169-5778.
Serena RothMontefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York.
Chenshu ZhangMontefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York.
Aaron BurkenroadUniversity of California Los Angeles, Los Angeles, California.
Gianni CarrozziMontefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York.
Joanna L StarrelsMontefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York.
Albert Einstein College of Medicine · USUniversity of California, Los Angeles · US

Funding

Mentoring Junior Investigators to Tackle the Opioid EpidemicK24DA046309 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STARRELS, JOANNA L. · 2018 to 2023
$876k
NIDA NIH HHS K24 DA046309
6 · The paper itself

Abstract

backgroundTo provide Centers for Disease Control and Prevention (CDC) guideline-recommended practices for patients on long-term opioid therapy (LTOT) including individualized decisions about opioid dose reduction, we developed the Power Over Pain (POP) Clinic.

objectiveTo describe frequency and reasons for opioid dose reduction and pre-post adherence to CDC guideline-recommended practices.

designRetrospective chart review with qualitative and pre-post analysis. PATIENTS AND

settingPatients at an urban internal medicine teaching practice-prescribed LTOT were seen at POP Clinic at least once.

methodsOpioid dose reduction was defined by reduction in morphine-equivalent daily dose (MEDD) at 6 and 12 months after the first POP Clinic visit compared to baseline using paired t-tests. Among patients with a dose reduction, reasons documented in POP Clinic notes were qualitatively examined. Dichotomous measures of receiving four CDC guideline-recommended practices (controlled substance agreement [CSA], urine drug testing [UDT], prescription monitoring program review, and naloxone dispensing) at baseline versus 6 and 12 months were compared using McNemar's tests.

resultsOf the 70 patients, most were female (66 percent) and Hispanic (54 percent). Forty-three patients (61 percent) had an opioid dose reduction in 12 months after the first POP Clinic visit. The most frequent reason was low or unclear benefit of continuing the current dose (49 percent). Mean MEDD was reduced from 69 mg to 57 mg at 6 months (p < 0.01) and to 56 mg at 12 months (p < 0.01). Completing a CSA, UDT, and naloxone distribution increased at 6 and 12 months (p < 0.01).

conclusionsIndividualized risk assessment in a primary care-based opioid management clinic is feasible and can result in opioid dose reduction and guideline adherence.

Indexed as

Analgesics, OpioidChronic PainDrug TaperingFemaleGuideline AdherenceHumansPrimary Health CareRetrospective StudiesAnalgesics, Opioid

Identifiers

PMID34904696
PMCPMC9885983
OpenAlexW4200054846

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.