Trial reportBJS open2021
Negative-pressure wound therapy after stoma reversal in colorectal surgery: a randomized controlled trial.
Trial report in BJS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Pooled it
- Negative-pressure wound therapy in thoracic and abdominal surgery: meta-analysis of randomized trials.BJS open · 2026Pooled it
- The use of negative pressure wound therapy following stoma reversal: a systematic review and meta-analysis of randomized controlled trials.International journal of colorectal disease · 2025Pooled it
- Risk factors and incidence of surgical wound infection after stoma reversal: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Gunsight closure versus conventional techniques for reversal of protective stoma after rectal cancer surgery: a propensity score matching study.International journal of colorectal disease · 2026Article
- Negative pressure wound therapy for preventing wound complications following stoma reversal: A systematic review and meta-analysis of randomized controlled trials.Asia-Pacific journal of oncology nursing · 2025Review
- An update on "The use of negative pressure wound therapy following stoma reversal: a systematic review and meta-analysis of randomized controlled trials" by Drumm et al.International journal of colorectal disease · 2025Article
- Effectiveness of negative pressure wound therapy (NPWT) in preventing incisional surgical site infection after stoma closure: a single institutional retrospective study.Surgery today · 2025Article
- Comparison of Negative Pressure Wound Therapy Systems and Conventional Non-Pressure Dressings on Surgical Site Infection Rate After Stoma Reversal: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of clinical medicine · 2025Review
- Mechanically powered negative pressure dressing reduces surgical site infection after stoma reversal.Surgery open science · 2025Article
- A Review Article: The Relationship Between Obesity and Colorectal Cancer.Current diabetes reports · 2024Review
- Preliminary results of Polish national multicenter study on colostomy reversal - LICO (Liquidation of Colostomy) study.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024Article
- A case series of prophylactic negative pressure wound therapy use with purse-string closure in stoma closure wounds in infants.Surgical case reports · 2024Article
- Clinical Benefits of Reducing Dead Space Using a Closed Suction Drain and Subcutaneous Large-bite Buried Suture Technique to Prevent Superficial Surgical-site Infections Following Primary Closure of a Diverting Stoma.Journal of the anus, rectum and colon · 2024Article
- Negative Pressure Wound Therapy in Closed Colorectal Surgical Incisions: A Systematic Review and Meta-Analysis.Cureus · 2023Review
- Risk factors analysis of surgical site infections in postoperative colorectal cancer: a nine-year retrospective study.BMC surgery · 2023Article
- The effectiveness of negative-pressure wound therapy for wound healing after stoma reversal: a randomized control study.Annals of surgical treatment and research · 2023Article
- Risk factor for the development of surgical site infection following ileostomy reversal: a single-center report.Updates in surgery · 2022Article
- Application of PREVENA (Surgical Incision Protection System) in reducing surgical site infections following reversal of ileostomy or colostomy: the PRIC study protocol.International journal of colorectal disease · 2022Article
- Delayed Primary Skin Closure Followed by Single-use Negative-pressure Wound Therapy Is Optimal for Wound Management After Bowel-stoma Reversal.In vivo (Athens, Greece)Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStoma-reversal surgery is associated with high postoperative morbidity, including wound complications and surgical-site infections (SSIs). This study aims to assess whether the application of negative-pressure wound therapy (NPWT) can improve wound healing compared with conventional wound dressing.
methodsThis was a single-centre, superiority, open-label, parallel, individually randomized controlled trial. Patients undergoing stoma reversal were randomized (1 : 1) to receive NPWT or conventional wound dressing. The primary endpoint of the study was the rate of wound complications and SSIs after stoma closure. The secondary endpoints were postoperative wound pain, rate of wound healing after 30 days from stoma closure, and wound aesthetic satisfaction.
resultsBetween June 2019 and January 2021, 50 patients were allocated to the NPWT group (all received NPWT, 49 were analysed); 50 patients were allocated to the conventional wound dressing group (48 received the treatment, 45 were analysed). No significant difference was found in wound-complication rate (10 per cent NPWT versus 16 per cent controls; odds ratio 0.61 (95 per cent c.i. 0.18 to 2.10), P = 0.542) and incisional SSI rate (8 per cent NPWT versus 7 per cent controls; odds ratio 1.24 (95 per cent c.i. 0.26 to 5.99), P = 1.000). The NPWT group showed less pain, higher aesthetic satisfaction (P < 0.0001), and a higher proportion of wound healing (92 versus 78 per cent; P = 0.081) compared with the control group.
conclusionNPWT does not reduce the incidence of SSI after stoma-reversal surgery compared with conventional wound dressing. However, NPWT improved the healing of uninfected wounds, reduced wound pain and led to better aesthetic outcomes.Registration number: NCT037812016 (clinicaltrials.gov).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.