Evidence map›Paper›PMID 34904116›Full record

ArticleOpen forum infectious diseases2021

A High Frequency of

Ekadashi Rajni, Ashutosh Singh, Bansidhar Tarai, Kusum Jain, Ravi Shankar, Kalpana Pawar, Vedprakash Mamoria, Anuradha Chowdhary

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. TheHealth science reports · 2024
    Article
  11. ISCCM Position Statement on the Management of Invasive Fungal Infections in the Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  12. Article
  13. Unresolved issues in the diagnosis of catheter related candidemia: A position paper.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024
    Review
  14. Review
  15. SevereJournal of intensive medicine · 2023
    Review
  16. Annual review of microbiology · 2023
    Review
  17. Molecular Detection ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Review
  20. Invasive Fungal Infections Associated with COVID-19.Journal of fungi (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ekadashi RajniDepartment of Microbiology, Mahatma Gandhi University of Medical Science & Technology, Jaipur, Rajasthan, India.
Ashutosh SinghMedical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.ORCID https://orcid.org/0000-0002-6807-7130
Bansidhar TaraiDepartment of Microbiology, Max Hospital, New Delhi, India.
Kusum JainMedical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Ravi ShankarDepartment of Biostatistics, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Kalpana PawarMedical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
Vedprakash MamoriaDepartment of Microbiology, Mahatma Gandhi University of Medical Science & Technology, Jaipur, Rajasthan, India.
Anuradha ChowdharyMedical Mycology Unit, Department of Microbiology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.ORCID https://orcid.org/0000-0002-2028-7462
University of Delhi · INGandhi Medical College & Hospital · INMax Healthcare · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ongoing pandemic of coronavirus disease 2019 (COVID-19) has overwhelmed healthcare facilities and raises an important novel concern of nosocomial transmission of

methodsWe evaluated the incidence and risk factors for development of candidemia in 2384 COVID-19 patients admitted during August 2020-January 2021 in ICUs of 2 hospitals (Delhi and Jaipur) in India. A 1:2 case-control matching was used to identify COVID-19 patients who did not develop candidemia as controls.

resultsA total of 33 patients developed candidemia and accounted for an overall incidence of 1.4% over a median ICU stay of 24 days. A 2-fold increase in the incidence of candidemia in COVID-19 versus non-COVID-19 patients was observed with an incidence rate of 14 and 15/1000 admissions in 2 ICUs.

conclusionsSecondary bacterial infections have been a concern with the use of tocilizumab. In this cohort of critically ill COVID-19 patients, tocilizumab was associated with the development of candidemia. Surveillance of antifungal resistance is warranted to prevent transmission of multidrug-resistant strains of nosocomial yeasts in COVID-19 hospitalized patients.

Indexed as

Candida aurisCandida tropicalisCOVID-19nosocomial infectionstocilizumab

Identifiers

PMID34904116
PMCPMC8522362
OpenAlexW3197491644

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.