Evidence map›Paper›PMID 34904115›Full record

ArticleBioMed research international2021

The Predictive Model of Oral Squamous Cell Survival Carcinoma: A Methodology of Validation.

Wan Muhamad Amir W Ahmad, Muhammad Azeem Yaqoob, Nor Farid Mohd Noor, Farah Muna Mohamad Ghazali, Nuzlinda Abdul Rahman, Liszen Tang, Nor Azlida Aleng, Mohammad Khursheed Alam

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In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wan Muhamad Amir W AhmadSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia (USM), 16150 Kubang Kerian, Kota Bharu, Kelantan, Malaysia.ORCID https://orcid.org/0000-0003-2366-3918
Muhammad Azeem YaqoobSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia (USM), 16150 Kubang Kerian, Kota Bharu, Kelantan, Malaysia.
Nor Farid Mohd NoorFaculty of Medicine, Universiti Sultan Zainal Abidin (UniSZA), Medical Campus, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Terengganu, Malaysia.
Farah Muna Mohamad GhazaliSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia (USM), 16150 Kubang Kerian, Kota Bharu, Kelantan, Malaysia.
Nuzlinda Abdul RahmanSchool of Mathematical Sciences, Universiti Sains Malaysia (USM), 11800 Pulau Pinang, Malaysia.
Liszen TangSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia (USM), 16150 Kubang Kerian, Kota Bharu, Kelantan, Malaysia.ORCID https://orcid.org/0000-0002-0573-3700
Nor Azlida AlengFaculty of Ocean Engineering Technology and Informatics, Universiti Malaysia Terengganu (UMT), 21030 Kuala Nerus, Terengganu, Malaysia.
Mohammad Khursheed AlamCollege of Dentistry, Jouf University, Sakaka, Saudi Arabia.ORCID https://orcid.org/0000-0001-7131-1752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is primarily caused by smoking, alcohol, betel quit, a series of genetic alterations, and epigenetic abnormalities in signaling pathways, which result in a variety of phenotypes that favor the development of OSCC. Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer, accounting for 80-90% of all oral malignant neoplasms. Oral cancer is relatively common, and it is frequently curable when detected and treated early enough. The tumor-node-metastasis (TNM) staging system is used to determine patient prognosis; however, geographical inaccuracies frequently occur, affecting management.

objectiveTo determine the additional relationship between factors discovered by searching for sociodemographic and metastasis factors, as well as treatment outcomes, which could help improve the prediction of the survival rate in cancer patients.

resultsThe statistical strategy showed R demonstrates that regression modeling outperforms an R-squared. It demonstrated that when data is partitioned into a training and testing dataset, the hybrid model technique performs better at predicting the outcome. The variable validation was determined using the well-established bootstrap-integrated MLR technique. In this case, three variables are considered: age, treatment, and distant metastases. It is important to note that three things affect the hazard ratio: age (

conclusionIn this study, a hybrid approach combining bootstrapping and multiple linear regression will be developed and extensively tested. The R syntax for this methodology was designed to ensure that the researcher completely understood the illustration. In this case, a hybrid model demonstrates how this critical conclusion enables us to better understand the utility and relative contribution of the hybrid method to the outcome. The statistical technique used in this study, R, demonstrates that regression modeling outperforms R-squared values of 0.9014 and 0.00882 for the predicted mean squared error, respectively. The conclusion of the study establishes the superiority of the hybrid model technique used in the study.

Indexed as

Cell SurvivalHumansLinear ModelsLymphatic MetastasisMalaysiaMouth NeoplasmsMultivariate AnalysisPrognosisProportional Hazards ModelsRetrospective StudiesRisk FactorsSquamous Cell Carcinoma of Head and NeckSurvival Rate

Identifiers

PMID34904115
PMCPMC8665892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.