ArticleWorld journal of hepatology2021
Incidence of umbilical vein catheter-associated thrombosis of the portal system: A systematic review and meta-analysis.
Article in World journal of hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Analysis of portal vein thrombosis prevalence and risk factors in neonates following umbilical venous catheterization: a systematic review and meta-analysis.Jornal de pediatriaPooled it
- Management of umbilical venous and arterial catheter: Neonatal European Vascular Access Team- ESPR Recommendation 2.Pediatric research · 2026Article
- Review of Artificial Intelligence for Automated Assessment of Lines, Drains, and Airways on Pediatric and Adult Chest Radiographs.Pediatric reports · 2026Review
- Venous Thromboembolism in Neonates, Children, and Adolescents: A Comprehensive Narrative Review of Risk Factors, Diagnosis, Treatment, and Prevention.Medicina (Kaunas, Lithuania) · 2026Review
- Umbilical venous catheter tip position and risk of portal vein thrombosis in neonates: a retrospective cohort study.Pediatric surgery international · 2026Article
- Analysis of risk factors and prognostic differences in hospital-acquired thrombosis between very preterm infants and moderate to late preterm infants.Frontiers in pediatrics · 2026Article
- A Prospective Study on the Systematic Application of the Safe Insertion Umbilical Venous Catheter (SIUVeC) Bundle.Children (Basel, Switzerland) · 2025Article
- Radiology resident proficiency in identifying misplaced lines, tubes, and devices: a simulation-based study using WIDI SIM.Emergency radiology · 2025Article
- Article
- Utility of point-of-care ultrasound of the liver in the neonatal intensive care unit: experience from a case series.Frontiers in pediatrics · 2025Article
- Portal Hypertension Unmasked-Cavernous Transformation of the Portal Vein Following Portal Vein Thrombosis in a 9-Year-Old Female: A Case Report.Clinical case reports · 2025Article
- Modified Kasai operation combined with autologous bone marrow mononuclear cell infusion for biliary atresia.BMC surgery · 2024Article
- Assessment of the clinical and laboratory risk factors for thrombosis in neonates admitted to neonatal intensive care unit (two Egyptian tertiary centers experience).Annals of hematology · 2024Article
- Reducing umbilical catheter migration rates by using a novel securement device.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Portal Hypertension in Children: Investigating Umbilical Catheterization in the Neonatal Period.Cureus · 2024Article
- Central Lines and Their Complications in Neonates: A Case Report and Literature Review.Children (Basel, Switzerland) · 2023Review
- Angiographic patterns of portal venous system in children with extrahepatic portal hypertension and its etiological and clinical relevance.Pediatric surgery international · 2023Article
- Indications, Measurements, and Complications of Ten Essential Neonatal Procedures.International journal of pediatrics · 2023Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of umbilical venous catheters (UVCs) in the perinatal period may be associated with severe complications, including the occurrence of portal vein thrombosis (PVT).
aimTo assess the incidence of UVC-related PVT in infants with postnatal age up to three months.
methodsA systematic and comprehensive database searching (PubMed, Cochrane Library, Scopus, Web of Science) was performed for studies from 1980 to 2020 (the search was last updated on November 28, 2020). We included in the final analyses all peer-reviewed prospective cohort studies, retrospective cohort studies and case-control studies. The reference lists of included articles were hand-searched to identify additional studies of interest. Studies were considered eligible when they included infants with postnatal age up to three months with UVC-associated PVT. Incidence estimates were pooled by using random effects meta-analyses. The quality of included studies was assessed using the Newcastle-Ottawa scale. The systematic review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) guidelines.
resultsOverall, 16 studies were considered eligible and included in the final analyses. The data confirmed the relevant risk of UVC-related thrombosis. The mean pooled incidence of such condition was 12%, although it varied across studies (0%-49%). In 15/16 studies (94%), diagnosis of thrombosis was made accidentally during routine screening controls, whilst in 1/16 study (6%) targeted imaging assessments were carried out in neonates with clinical concerns for a thrombus. Tip position was investigated by abdominal ultrasound (US) alone in 1/16 (6%) studies, by a combination of radiography and abdominal US in 14/16 (88%) studies and by a combination of radiography, abdominal US and echocardiography in 1/16 (6%) studies.
conclusionTo the best of our knowledge, this is the first systematic review specifically investigating the incidence of UVC-related PVT. The use of UVCs requires a high index of suspicion, because its use is significantly associated with PVT. Well-designed prospective studies are required to assess the optimal approach to prevent UVC-related thrombosis of the portal system.
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