Evidence map›Paper›PMID 34904014›Full record

ArticleIranian journal of pharmaceutical research : IJPR2021

Anticancer Activity of Ethnopharmacological Plants of Golestan Province/Iran against AGS, HT-29 and KYSE-30 Cell Lines through Promoting the Apoptosis and Immunomodulatory Effects.

Mahdieh Naghavi Alhosseini, Masoumeh Mazandarani, Ayesheh Enayati, Mohsen Saiedi, Homa Davoodi

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Authenticating the geographic origins ofFrontiers in plant science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mahdieh Naghavi AlhosseiniLaboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Masoumeh MazandaraniDepartment of Botany, Islamic Azad University, Gorgan Branch, Gorgan, Iran.
Ayesheh EnayatiIschemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Mohsen SaiediStem Cell Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Homa DavoodiCancer Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Golestan University of Medical Sciences · IRGolestan University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anticancer and immunomodulatory effects of medicinal plants from Golestan province, as a promising source of cancer therapy against gastrointestinal cancer cell lines, were investigated in this study. The ethanolic root/aerial part extracts of 9 medicinal plants were screened for their cytotoxicity against normal mouse fibroblast cells (L-929) and three human cancer cell lines including gastric adenocarcinoma (AGS), colorectal adenocarcinoma (HT-29), and esophagus adenocarcinoma (KYSE-30) by performing MTT assay to determine the IC50 of the extracts. The

Indexed as

AKT/ ERKCytotoxicityEthnopharmacological plantsGastrointestinal cancerNFκBTLR-4

Identifiers

PMID34904014
PMCPMC8653648
OpenAlexW3213211608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.