Evidence map›Paper›PMID 34904012›Full record

ArticleIranian journal of pharmaceutical research : IJPR2021

Evaluation of Inflammasome Activation in Peripheral Blood Mononuclear Cells of Hemodialysis Treated Patients with Glomerulonephritis.

Atieh Hashemi, Razieh Bigdeli, Masoumeh Shahnazari, Farshid Oruji, Somayeh Fattahi, Erfan Panahnejad, Ayda Ghadri, Elmira Movahedi-Asl, Masoumeh Mahdavi-Ourtakand, Vahid Asgary and 1 more

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Advances in applications of siRNA in cancer therapy: challenges and opportunities.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
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  12. Knockdown of SIX4 inhibits pancreatic cancer cells via apoptosis induction.Medical oncology (Northwood, London, England) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Atieh HashemiDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Razieh BigdeliResearch and Development Laboratory, Javid Biotechnology Institute, Tehran, Iran.
Masoumeh ShahnazariResearch and Development Laboratory, Javid Biotechnology Institute, Tehran, Iran.
Farshid OrujiDepartment of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.
Somayeh FattahiDepartment of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.
Erfan PanahnejadResearch and Development Laboratory, Javid Biotechnology Institute, Tehran, Iran.
Ayda GhadriDepartment of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.
Elmira Movahedi-AslDepartment of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.
Masoumeh Mahdavi-OurtakandDepartment of Biology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.
Vahid AsgaryResearch and Development Laboratory, Javid Biotechnology Institute, Tehran, Iran.
Fahimeh Baghbani-AraniDepartment of Genetics and Biotechnology, School of Biological Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.
Islamic Azad University of Varamin · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, it has been found that abnormal activation of inflammasomes, the intracellular multiprotein complexes, plays an important role in the pathogenesis and the development of inflammatory diseases. To determine whether the NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is involved in chronic inflammatory condition reported in glomerulonephritic- hemodialysis (HD) patients, we investigated the mRNA levels of

Indexed as

GlomerulonephritisHemodialysisInflammasomesNLRC4NLRP3

Identifiers

PMID34904012
PMCPMC8653650
OpenAlexW3201122308

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.