ArticleScientific reports2021
Antimicrobial activity of a novel Spanish propolis against planktonic and sessile oral Streptococcus spp.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Effects of propolis-modified glass ionomer cement on antimicrobial activity and physico-mechanical properties: a systematic review.Odontology · 2026Pooled it
- Caffeic Acid Phenethyl Ester Suppresses Adhesion to Mediate Its Antibiofilm Activity Against Methicillin-ResistantMicroorganisms · 2026Article
- Antimicrobial Activity of Ethanolic Propolis Extracts from Tame (Arauca) on Oral Biofilm Co-Cultures.Pathogens (Basel, Switzerland) · 2025Article
- Antimicrobial Activities of Propolis Nanoparticles in Combination with Ampicillin Sodium Against Methicillin-ResistantMicroorganisms · 2025Article
- Article
- Investigating the Effect of Photodynamic Therapy With a 660 nm Laser With Methylene Blue and Cold Atmospheric Plasma Therapy onJournal of lasers in medical sciences · 2025Article
- Propolis in Dental Implantology: A Systematic Review of Its Effects and Benefits.Journal of functional biomaterials · 2024Review
- Gallic acid exerts antibiofilm activity by inhibiting methicillin-resistant Staphylococcus aureus adhesion.Scientific reports · 2024Article
- Anti-Biofilm Perspectives of Propolis againstBiomolecules · 2024Article
- Propolis Use in Dentistry: A Narrative Review of Its Preventive and Therapeutic Applications.International dental journal · 2024Review
- Review
- Cell wall disruption, membrane damage, and decrease in the expression of Yrp1 virulence factor inIranian journal of microbiology · 2023Article
- Overview of strategies to improve the antibacterial property of dental implants.Frontiers in bioengineering and biotechnology · 2023Review
- Antifungal and Immunomodulatory Ingredients from Traditional Chinese Medicine.Antibiotics (Basel, Switzerland) · 2022Review
- Antibacterial and Antibiofilm Activity of Carvacrol against Oral Pathogenic Bacteria.Metabolites · 2022Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased bacterial resistance to traditional antimicrobial agents has prompted the use of natural products with antimicrobial properties such as propolis, extensively employed since ancient times. However, the chemical composition of propolis extracts is extremely complex and has been shown to vary depending on the region and season of collection, due to variations in the flora from which the pharmacological substances are obtained, being therefore essential for their antimicrobial activity to be checked before use. For this purpose, we evaluate the in vitro antimicrobial and anti-biofilm activity of a new and promising Spanish ethanolic extract of propolis (SEEP) on Streptococcus mutans and Streptococcus sanguinis, responsible, as dominant 'pioneer' species, for dental plaque. Results reveal that S. sanguinis is more sensitive to SEEP, slowing and retarding its growth considerably with lower concentrations than those needed to produce the same effect in S. mutans. SEEP presents concentration- and time-dependent killing activity and, furthermore, some of the subinhibitory concentrations employed increased biofilm formation even when bacterial growth decreased. Mono and dual-species biofilms were also inhibited by SEEP. Findings obtained clearly show the relevance of using biofilm and subinhibitory concentration models to determine optimal treatment concentrations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.