Evidence map›Paper›PMID 34903770›Full record

ArticleScientific reports2021

Full-thickness macular hole formation in proliferative diabetic retinopathy.

Mei-Chi Tsui, Yi-Ting Hsieh, Tso-Ting Lai, Chun-Ting Lai, Hsuan-Chieh Lin, Tzyy-Chang Ho, Chang-Hao Yang, Chung-May Yang, Lu-Chun Wang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Refining vitrectomy for proliferative diabetic retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mei-Chi TsuiDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Yi-Ting HsiehDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Tso-Ting LaiDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Chun-Ting LaiDepartment of Ophthalmology, Eye Center, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Hsuan-Chieh LinDepartment of Ophthalmology, National Taiwan University Hospital Hsinchu Branch, Hsinchu, Taiwan.
Tzyy-Chang HoDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Chang-Hao YangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Chung-May YangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Lu-Chun WangDepartment of Ophthalmology, National Taiwan University Hospital Yunlin Branch, No. 579, Sec. 2, Yunlin Rd., Douliou, Yunlin County, Taiwan. cmcboy2000@gmail.com.
National Taiwan University Hospital · TWChina Medical University · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty-one consecutive patients (21 eyes) having proliferative diabetic retinopathy (PDR) and fibrovascular proliferation (FVP) with optical coherence tomography (OCT) available before and after full-thickness macular hole (FTMH) formation were retrospectively reviewed. Four types of FTMH formation pathways in PDR were identified and were quite different from those in idiopathic conditions. The activity, severity and locations of FVP varied in PDR eyes destined to develop FTMHs. Type 1 was characterized by epiretinal membrane (ERM) and/or vitreomacular traction (VMT) inducing foveoschisis, intraretinal cysts or foveal detachment, followed by formation of a FTMH or macular hole retinal detachment (MHRD). In type 2, ERM and/or FVP induced lamellar macular hole (LMH) with foveoschisis, followed by the formation of FTMH or MHRD. Type 3 was characterized by the initial tractional retinal detachment (TRD) with foveal cysts and/or foveoschisis and the subsequent formation of MHRD. Type 4 was characterized by TRD associated with foveal thinning, ensued by the formation of MHRD. The severity of FVP was grade 2 in 66.7% of eyes in both types 1 and 4, and grade 3 in 75% of eyes in type 3 while the severity of FVP was more evenly distributed in type 2.

Indexed as

AdultAgedDiabetic RetinopathyEpiretinal MembraneFemaleHumansMaleMiddle AgedRetinal DetachmentRetinal PerforationsTomography, Optical Coherence

Identifiers

PMID34903770
PMCPMC8668955
OpenAlexW4225366687

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.