Evidence map›Paper›PMID 34903540›Full record

ArticleBMJ open2021

Sleep and daytime problems during the COVID-19 pandemic and effects of coronavirus infection, confinement and financial suffering: a multinational survey using a harmonised questionnaire.

Markku Partinen, Brigitte Holzinger, Charles M Morin, Colin Espie, Frances Chung, Thomas Penzel, Christian Benedict, Courtney J Bolstad, Jonathan Cedernaes, Rachel Ngan Yin Chan and 15 more

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06341374 (Impact of Sleep Disorders on Innate Immunity in COVID-19 Patients. A Cohort Study), which is not on this map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06341374 unknown statusnot on this mapstarted 2023, after this paper: background citation

Impact of Sleep Disorders on Innate Immunity in COVID-19 Patients. A Cohort Study

Typeobservational_patient_registrySponsorParc Taulí Hospital UniversitariRan2023 to 2024Enrolled50ConditionsApnea, Obstructive Sleep, SARS CoV 2 InfectionArmsInfluvac Tetra
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Observational
  5. Article
  6. Review
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  9. Article
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  12. Unfolding the role of exercise in the management of sleep disorders.European journal of applied physiology · 2024
    Review
  13. Article
  14. Article
  15. Habitual short sleepers with pre-existing medical conditions are at higher risk of Long COVID.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  16. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Markku PartinenDepartment of Clinical Neurosciences, University of Helsinki Clinicum Unit, Helsinki, Finland markku.partinen@helsinki.fi.ORCID 0000-0002-8182-9368
Brigitte HolzingerInstitute for Dream and Consciousness Research, Medical University of Vienna, Wien, Austria.
Charles M MorinCentre d'étude des troubles du sommeil, Centre de recherche CERVO/Brain Research Center, Université Laval École de psychologie, Quebec, Quebec, Canada.
Colin EspieSleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Frances ChungDepartment of Anesthesiology and Pain Medicine, University Health Network, Toronto, Ontario, Canada.ORCID 0000-0001-9576-3606
Thomas PenzelSleep Medicine Center, Charite University Hospital Berlin, Berlin, Germany.ORCID 0000-0002-4304-0112
Christian BenedictDepartment of Neuroscience, Sleep Science (BMC), Uppsala University, Uppsala, Sweden.
Courtney J BolstadDepartment of Psychology, Mississippi State University, Mississippi State, Mississippi, USA.
Jonathan CedernaesDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Rachel Ngan Yin ChanLi Chiu Kong Family Sleep Assessment Unit, Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Yves DauvilliersNational Reference Center for Narcolepsy, Sleep and Wake Unit, Department of Neurology, Gui-de-Chauliac Hospital, University Hospital Centre Montpellier, Montpellier, France.
Luigi De GennaroDepartment of Psychology, Sapienza University of Rome, Roma, Lazio, Italy.
Fang HanDepartment of Pulmonary Medicine, Peking University People's Hospital, Beijing, China.
Yuichi InoueDepartment of Somnology, Tokyo Medical University, Shinjuku-ku, Japan.
Kentaro MatsuiDepartment of Clinical Laboratory and Department of Sleep-Wake Disorders, National Center of Neurology and Psychiatry National Institute of Mental Health, Kodaira, Japan.
Damien LegerSleep and Vigilance Center, Hopital Hotel-Dieu de Paris, Paris, France.
Ana Suely CunhaProduction Engineering Department, Federal University of Rio Grande do Norte, Natal, Brazil.
Ilona MerikantoResearch Programs Unit, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Sergio Mota-RolimBrain Institute, Onofre Lopes University Hospital, Petropolis, Brazil.
Michael NadorffDepartment of Psychology, Mississippi State University, Mississippi State, Mississippi, USA.
Giuseppe PlazziIRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.
Jules SchneiderSleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Mariusz SieminskiDepartment of Emergency Medicine, Medical University of Gdansk, Gdansk, Poland.
Yun-Kwok WingLi Chiu Kong Family Sleep Assessment Unit, Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Bjørn BjorvatnDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.ORCID 0000-0001-7051-745X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSleep is important for human health and well-being. No previous study has assessed whether the COVID-19 pandemic impacts sleep and daytime function across the globe.

methodsThis large-scale international survey used a harmonised questionnaire. Fourteen countries participated during the period of May-August 2020. Sleep and daytime problems (poor sleep quality, sleep onset and maintenance problems, nightmares, hypnotic use, fatigue and excessive sleepiness) occurring 'before' and 'during' the pandemic were investigated. In total, 25 484 people participated and 22 151 (86.9%) responded to the key parameters and were included. Effects of COVID-19, confinement and financial suffering were considered. In the fully adjusted logistic regression models, results (weighted and stratified by country) were adjusted for gender, age, marital status, educational level, ethnicity, presence of sleep problems before COVID-19 and severity of the COVID-19 pandemic in each country at the time of the survey.

resultsThe responders were mostly women (64%) with a mean age 41.8 (SD 15.9) years (median 39, range 18-95). Altogether, 3.0% reported having had COVID-19; 42.2% reported having been in confinement; and 55.9% had suffered financially. All sleep and daytime problems worsened during the pandemic by about 10% or more. Also, some participants reported improvements in sleep and daytime function. For example, sleep quality worsened in about 20% of subjects and improved in about 5%. COVID-19 was particularly associated with poor sleep quality, early morning awakening and daytime sleepiness. Confinement was associated with poor sleep quality, problems falling asleep and decreased use of hypnotics. Financial suffering was associated with all sleep and daytime problems, including nightmares and fatigue, even in the fully adjusted logistic regression models.

conclusionsSleep problems, fatigue and excessive sleepiness increased significantly worldwide during the first phase of the COVID-19 pandemic. Problems were associated with confinement and especially with financial suffering.

Indexed as

COVID-19PandemicsAdultFemaleHumansSARS-CoV-2Sleep QualitySurveys and Questionnairesanxiety disordersCOVID-19epidemiologyneurologysleep medicinesocial medicine

Identifiers

PMID34903540
PMCPMC8671846

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.