Evidence map›Paper›PMID 34903490›Full record

ArticleJournal of plastic, reconstructive & aesthetic surgery : JPRAS2022

Nasal skin reconstruction: Time to rethink the reconstructive ladder?

Inge J Veldhuizen, Philip Brouwer, Abdullah Aleisa, Nicholas R Kurtansky, Stephen W Dusza, Kishwer S Nehal, Maarten M Hoogbergen, René R W J van der Hulst, Erica H Lee

Open access · greenAbstract read
In one paragraph

Article in Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Descending the Reconstruction Ladder: Single-Stage Full-Thickness Skin Grafting for Wide Nasal Skin Malignant Defects.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2025
    Article
  4. Smartphone-based thermal imaging for pedicled skin flaps: a pilot study toward objective perfusion assessment in facial, head, and neck reconstruction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  5. Reconstruction of Small Nasal Defects.Seminars in plastic surgery · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Inge J VeldhuizenDermatology Division, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Plastic Surgery, Catharina Hospital, Eindhoven, The Netherlands.
Philip BrouwerDepartment of Plastic Surgery, Catharina Hospital, Eindhoven, The Netherlands.
Abdullah AleisaDermatology Division, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nicholas R KurtanskyDermatology Division, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Stephen W DuszaDermatology Division, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Kishwer S NehalDermatology Division, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Maarten M HoogbergenDepartment of Plastic Surgery, Catharina Hospital, Eindhoven, The Netherlands.
René R W J van der HulstDepartment of Plastic and Reconstructive Surgery, Nutrim, Maastricht University Medical Center, Maastricht, The Netherlands.
Erica H LeeDermatology Division, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: leee@mskcc.org.
Memorial Sloan Kettering Cancer Center · USRadboud University Nijmegen · NLMaastricht University · NL

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundNasal scarring can compromise aesthetics and function given its complex three-dimensional structure and central location. This study aimed to measure patients' satisfaction after reconstruction for nasal defects following Mohs micrographic surgery.

methodsPatients presenting with nasal nonmelanoma skin cancer at Memorial Sloan Kettering Cancer Center New York, USA and Catharina Hospital Eindhoven, Netherlands from April 2017 to November 2019 were asked to participate. Reconstruction type, complications, and patients satisfaction were assessed. Patients completed the FACE-Q Skin Cancer - Satisfaction with Facial Appearance scale (preoperative and 1-year postoperative) and the Appraisal of Scars scale (1-year postoperative).

resultsA total of 128 patients completed the preand postoperative scales. There were 35 (27%) surgical defects repaired with primary closures, 71 (55.5%) with flaps, and 22 (17.2%) with full-thickness skin grafts (FTSG). Patients that underwent a flap or FTSG reconstruction had higher scar satisfaction scores than primary closures (p = 0.03). A trend was seen with patients following flap reconstructions scoring 7.8 points higher than primary closures and patients with upper nose defects scoring 6.4 points higher than lower nose defects. Males were significantly more satisfied than females. No significant difference was observed in the preoperative and postoperative facial appearance scores between the three groups (p = 0.39).

conclusionPatients are more satisfied in the long term with their scars after flap reconstructions compared to primary closures. Therefore, nasal skin reconstruction may not follow the traditional reconstructive ladder and more complex approaches may lead to higher long-term scar satisfaction.

Indexed as

Nose NeoplasmsPlastic Surgery ProceduresRhinoplastySkin NeoplasmsFemaleHumansMaleMohs SurgeryNoseSurgical FlapsFlapsGraftsNosePrimary closureReconstructionSatisfaction

Identifiers

PMID34903490
PMCPMC8976754
OpenAlexW3212200055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.