Evidence map›Paper›PMID 34903312›Full record

ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2022

Biochemical and Hematologic Reference Intervals for Anesthetized, Female, Juvenile Yorkshire Swine.

Nikolaos Dimitrakakis, Anna Waterhouse, Shanda Lightbown, Daniel C Leslie, Amanda Jiang, Dana E Bolgen, Kayla Lightbown, Kelly Cascio, Gabriela Aviles, Elizabeth Pollack and 7 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Journal of biomedical optics · 2026
    Article
  3. Article
  4. Effect of Anesthesia on Hematologic Parameters of Female Domestic Swine (Sus scrofa domestica).Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Analysis of growth rate, haematologic, and biochemical parameters of Oncopigs.International journal of veterinary science and medicine · 2025
    Article
  9. Review
  10. siRNA-mediated reduction of a circulating protein in swine using lipid nanoparticles.Molecular therapy. Methods & clinical development · 2024
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Nikolaos DimitrakakisWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Anna WaterhouseWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Shanda LightbownWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Daniel C LeslieWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Amanda JiangWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Dana E BolgenWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Kayla LightbownWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Kelly CascioWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Gabriela AvilesWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Elizabeth PollackAnimal Research, Boston Children's Hospital, Boston, Massachusetts.
Sam JurekWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Kathryn DonovanAnimal Research, Boston Children's Hospital, Boston, Massachusetts.
Julia B Hicks-BerthetWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Kazuo ImaizumiWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Michael SuperWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Donald E IngberWyss Institute for Biologically Inspired Engineering at Harvard University, Boston, Massachusetts.
Arthur NedderAnimal Research, Boston Children's Hospital, Boston, Massachusetts.
Harvard University · USBoston Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Swine are widely used in biomedical research, translational research, xenotransplantation, and agriculture. For these uses, physiologic reference intervals are extremely important for assessing the health status of the swine and diagnosing disease. However, few biochemical and hematologic reference intervals that comply with guidelines from the Clinical and Laboratory Standards Institute and the American Society for Veterinary Clinical Pathology are available for swine. These guidelines state that reference intervals should be determined by using 120 subjects or more. The aim of this study was to generate hematologic and biochemical reference intervals for female, juvenile Yorkshire swine (

Indexed as

Hematologic TestsAnimalsFemaleReference StandardsReference ValuesSwine

Identifiers

PMID34903312
PMCPMC8786382
OpenAlexW4200586937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.