Evidence map›Paper›PMID 34903251›Full record

ArticleTrials2021

Does virtual reality increase the efficacy of psychotherapy for young adults with mild-to-moderate depression? A study protocol for a multicenter randomized clinical trial.

Adrián Montesano, Joan C Medina, Clara Paz, Helena García-Mieres, Noelia Niño-Robles, Eugeni García-Grau, Josep Cañete Crespillo, Alejandro García-Gutiérrez, Miquel Alabèrnia-Segura, Guillem Feixas

2 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04321525 naterminatednot on this map

Psychotherapy for Young Adults With Mild-to-moderate Depression: Does Virtual Reality Increase Its Efficacy

TypeinterventionalSponsorUniversity of BarcelonaRan2021 to 2024Enrolled12ConditionsDepressionArmsCognitive-behavioral therapy, Personal Construct Therapy, Personal Construct Therapy with virtual reality
NCT06473155 narecruitingnot on this mapstarted 2024, after this paper: background citation

Discovering Adolescents' Talents and Life Projects as a Key Factor in Their Life Satisfaction

TypeinterventionalSponsorCentre BesaiRan2024 to 2025Enrolled90ConditionsHealthy, Adolescent DevelopmentArmsExperimental: Humanistic Integrative Psychotherapy and Identity Exploration (HIP+EYME), Experimental: Humanistic Integrative Psychotherapy, Identity, and Geniotype Exploration (HIP+EYME+GENIOTYPE)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Adrián MontesanoSchool of Psychology and Educational Sciences, Open University of Catalonia, Barcelona, Spain.
Joan C MedinaSchool of Psychology and Educational Sciences, Open University of Catalonia, Barcelona, Spain.
Clara PazSchool of Psychology and Education, Universidad de Las Américas, Quito, Ecuador. clara.paz@udla.edu.ec.ORCID http://orcid.org/0000-0003-1106-9567
Helena García-MieresResearch and Development Unit, Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain.
Noelia Niño-RoblesDepartment of Clinical Psychology and Psychobiology, Universitat de Barcelona, Barcelona, Spain.
Eugeni García-GrauDepartment of Clinical Psychology and Psychobiology, Universitat de Barcelona, Barcelona, Spain.
Josep Cañete CrespilloDepartment of Mental Health, Consorci Sanitari del Maresme, Hospital de Mataró, Mataró, Spain.
Alejandro García-GutiérrezDepartment of Clinical Psychology and Psychobiology, Universitat de Barcelona, Barcelona, Spain.
Miquel Alabèrnia-SeguraDepartment of Clinical Psychology and Psychobiology, Universitat de Barcelona, Barcelona, Spain.
Guillem FeixasDepartment of Clinical Psychology and Psychobiology, The Institute of Neurosciences, Universitat de Barcelona, Barcelona, Spain.
Universitat de Barcelona · ESUniversitat Oberta de Catalunya · ESCentro de Investigación Biomédica en Red de Salud Mental · ESMaresme Health Consortium · ESUniversidad de Las Américas · EC

Funding

Ministerio de Ciencia, Innovación y Universidades RTI2018-094294-B-I00
6 · The paper itself

Abstract

backgroundThe improvement of psychological treatments for depression in young adults is a pressing issue highlighted in the literature. Its relevance is determined not only because young adults are underrepresented in research, but also to prevent chronic severe mental health disorders later in life. Engagement is considered a key factor for a good therapeutic outcome, especially among young patients. In this sense, virtual reality could be particularly suited to engage young adults in the therapy process. This project aims to improve the psychological treatment of mild-to-moderate depression in young adults by testing out the efficacy of virtual reality-enhanced personal construct therapy (PCT-VR), as compared to personal construct therapy alone (PCT) and to the reference standard cognitive behavioral therapy (CBT). In contrast to CBT, PCT neither educates patients about depression nor gives them directions on the changes to be made in their dysfunctional behaviors or cognitions. Rather, PCT explores the coherence (or conflicts) of thoughts and behaviors with respect to the person's sense of identity and focuses on meaning-making processes.

methodsThe efficacy of this innovative intervention (PCT-VR) will be compared to PCT and to CBT in a randomized clinical trial. The study includes an appraisal of therapists' adherence and independent assessments to preserve internal validity. The Beck Depression Inventory-II is the primary outcome measure for calculating both statistical and clinical significance, but other outcomes will also be assessed (e.g., functioning, well-being, anxiety, stress) at pre- and post-therapy and at 6-month follow-up. The trial will be conducted in a naturalistic context, mostly at the usual health care center of each patient. A sample of 225 participants is targeted to reach enough statistical power to accomplish the goals of the study. DISCUSSION: We expect that providing evidence for PCT-VR will widen the repertoire of evidence-based technology-based psychotherapeutic interventions for young adults and contribute to the prevention of deteriorating courses of the disorder.

trial registrationClinicalTrials.gov NCT04321525 . Registered on 18 February 2020.

Indexed as

Cognitive Behavioral TherapyVirtual RealityDepressionHumansMulticenter Studies as TopicPsychotherapyRandomized Controlled Trials as TopicTreatment OutcomeYoung AdultCognitive behavioral therapyPersonal construct therapyPrevention, Psychotherapy efficacyRepertory grid techniqueSelf and identityTherapeutic allianceTherapy engagementVirtual reality

Identifiers

PMID34903251
PMCPMC8666832
OpenAlexW4225688089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.