Evidence map›Paper›PMID 34903226›Full record

ArticleJournal of nanobiotechnology2021

Biodegradable reduce expenditure bioreactor for augmented sonodynamic therapy via regulating tumor hypoxia and inducing pro-death autophagy.

Weijuan Zou, Junnian Hao, Jianrong Wu, Xiaojun Cai, Bing Hu, Zhigang Wang, Yuanyi Zheng

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Weijuan Zou *Department of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, People's Republic of China.
Junnian Hao *Department of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, People's Republic of China.
Jianrong WuDepartment of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, People's Republic of China. wujr_028@126.com.
Xiaojun CaiDepartment of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, People's Republic of China.
Bing HuDepartment of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, People's Republic of China.
Zhigang WangChongqing Key Laboratory of Ultrasound Molecular Imaging, Ultrasound Department of the Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Yuanyi ZhengDepartment of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, People's Republic of China. zhengyuanyi@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-1328-0641
Shanghai Jiao Tong University · CNDalian Medical University · CN

Funding

International Cooperation and Exchange Programme 81720108023Postdoctoral Research Foundation of China 2020M681331Postdoctoral Research Foundation of China 2021T140458Science and Technology Commission of Shanghai Municipality 2018YFC0115200the open project of State Key Laboratory of Oncogenes and Related Genes KF2104-93#Young Scientists Fund 82001943
6 · The paper itself

Abstract

backgroundsSonodynamic therapy (SDT) as an emerging reactive oxygen species (ROS)-mediated antitumor strategy is challenged by the rapid depletion of oxygen, as well as the hypoxic tumor microenvironment. Instead of the presently available coping strategies that amplify the endogenous O

resultsWe successfully fabricated the O

conclusionsThis work not only provides a reduce expenditure means for enduring SDT, but also represents an inquisitive strategy for tumor treatments by inducing pro-death autophagy.

Indexed as

Ultrasonic TherapyAnimalsAntineoplastic AgentsAutophagyBioreactorsFemaleHematoporphyrinsMiceMice, NudeNanoparticlesOrganosilicon CompoundsPolyethylene GlycolsReactive Oxygen SpeciesTumor HypoxiaAntineoplastic Agentshematoporphyrin monomethyl etherHematoporphyrinsOrganosilicon CompoundsPolyethylene GlycolsReactive Oxygen SpeciesBiodegradableHollow mesoporous organosilicaHypoxia regulationPro-death autophagySonodynamic therapy

Identifiers

PMID34903226
PMCPMC8670251
OpenAlexW4226199395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.